Cure My Disease

Don't miss your cure!

 Log in / Sign up

Can fish oil and metformin protect hearts in PCOS?

NCT ID NCT06424860

Recruiting now Disease control Sponsor: University of Alberta Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether taking fish oil and/or metformin for 12 months can improve heart health in women with Polycystic Ovary Syndrome (PCOS). PCOS raises the risk of heart disease and diabetes. The trial will enroll 146 women with PCOS who are overweight and have high blood fats or blood sugar. Researchers will measure changes in artery thickness, plaque, and heart function.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
fish oil and metformin
What this could lead to
If it works, this could point toward a simple, low-cost way to reduce heart disease risk in women with PCOS.
What could go wrong
This is an early phase 1 trial with a small number of participants, so results may not be conclusive or apply to everyone. The interventions are generally safe, but benefits may be modest.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ATHEROSCLEROTIC CARDIOVASCULAR DISEASE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

atherosclerosis atherosclerotic cardiovascular disease Cardiomegaly cardiovascular disorder Plaque, Atherosclerotic polycystic ovary syndrome type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATHEROSCLEROTIC CARDIOVASCULAR DISEASE ATHEROSCLEROTIC PLAQUE CARDIAC HYPERTROPHY CARDIOVASCULAR DISEASE PCOS

Contacts and locations

Locations

  • Human Nutrition Research Unit - Li Ka Shing Health Research Center

    RECRUITING

    Edmonton, Alberta, T6G 2E1, Canada

  • Mazankowski Alberta Heart Institute

    RECRUITING

    Edmonton, Alberta, T6G-2B7, Canada

  • University of Alberta Hospital - Division of Endocrinology

    RECRUITING

    Edmonton, Alberta, T6G-2B7, Canada

    Contact Email: •••••@•••••

More trials for these conditions

Other studies related to the condition(s) this trial covers.