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New hope for stubborn high cholesterol: pemafibrate trial launches

NCT ID NCT07634484

Recruiting now Disease control Sponsor: Kowa Company, Ltd. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 14, 2026 · Updated 2 times

Summary

This study tests a drug called pemafibrate in 120 adults with high cholesterol that remains high even after taking statins. Participants will take either a low or higher dose of pemafibrate or a placebo pill daily for 12 weeks. The goal is to see if pemafibrate can safely lower cholesterol levels further.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Pemafibrate
What this could lead to
If successful, pemafibrate could offer an additional treatment option for people with high cholesterol that is not fully controlled by statins alone.
What could go wrong
This is a relatively small, short-term study (12 weeks) testing a drug already on the market, so it is unlikely to lead to a major breakthrough. The benefit may be modest and not apply to everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Hypercholesterolemia hyperlipidemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HYPERCHOLESTEROLEMIA

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Ami Higashi Clinic

    RECRUITING

    Ibaraki, Japan

  • Hirose Clinic

    RECRUITING

    Saitama, Japan

  • Medical Corporation Asbo Tokyo Asbo Clinic

    RECRUITING

    Tokyo, Japan

  • Medical Corporation Heishinkai OCROM Clinic

    RECRUITING

    Osaka, Japan

  • Medical Corporation Heishinkai ToCROM Clinic

    RECRUITING

    Tokyo, Japan

  • Medical Corporation Shintokai Yokohama Minoru Clinic

    RECRUITING

    Kanagawa, Japan

  • Medical Corporation Yukeikai Asano Internal Medicine Clinic

    RECRUITING

    Saitama, Japan

  • NTT Medical Center Sapporo

    RECRUITING

    Hokkaido, Japan

  • Olive Takamatsu Medical Clinic

    RECRUITING

    Kagawa, Japan

  • Shimokitazawa Tomo Clinic

    RECRUITING

    Tokyo, Japan

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