Tighter blood pressure control may reduce brain aneurysm risk
NCT ID NCT05941377
First seen Jun 25, 2026 · Last updated Jun 30, 2026 · Updated 3 times
Summary
This study tested whether lowering blood pressure more aggressively than standard care reduces the risk of rupture or growth of unruptured brain aneurysms. 577 Chinese adults with small, unruptured aneurysms and high blood pressure were randomly assigned to keep their blood pressure below 120 mmHg (enhanced) or below 140 mmHg (standard). The researchers tracked aneurysm instability, including rupture, growth, or related symptoms, over 24 months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- blood pressure lowering (enhanced vs standard targets)
- What this could lead to
- If successful, this could show that tighter blood pressure control reduces the chance of a brain aneurysm rupturing or growing, offering a simple way to lower risk.
- What could go wrong
- This is a completed trial with 577 participants, but the results are not yet widely known. Tighter blood pressure control may increase the risk of ischemic events like stroke or heart attack.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Capital Medical University Affiliated Beijing Tiantan Hospital
Beijing, Beijing Municipality, China
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