UNRUPTURED INTRACRANIAL ANEURYSM

This study tests if a drug called indobufen works better than aspirin at preventing strokes and blood clots after a brain aneurysm is fixed with a stent or coil. About 2,500 people with unruptured brain aneurysms will take either indobufen or aspirin, plus clopidogrel, for 6 mont…

This early study tests a new device called the LuSeed Aneurysm Embolization System for treating unruptured brain aneurysms. The device is designed to block blood flow into the aneurysm, reducing the risk of rupture. About 30 adults aged 18-80 with unruptured saccular aneurysms wi…

This study tests a non-invasive device that gently stimulates a nerve in the ear to see if it can prevent headaches after a brain aneurysm procedure. About 440 adults will either get the real stimulation or a fake version. The goal is to find a safe, drug-free way to reduce pain …

This study follows 1,000 people with small, unruptured brain aneurysms (3-7 mm) for three years. Researchers will use MRI scans to see if a specific imaging sign—wall enhancement—can predict which aneurysms grow. The goal is to create a safer, personalized monitoring plan so that…

This study tests whether a 3D simulation software called Sim&Size can help doctors plan treatments for unruptured brain aneurysms more accurately than current 2D methods. About 576 adults will be randomly assigned to use the software or standard planning. Researchers will compare…

This observational study looks at proteins in tiny particles called extracellular vesicles from the blood of 120 people with brain aneurysms. Researchers will collect blood from different areas of the circulatory system during surgery to compare protein patterns. The goal is to f…