Brain aneurysm study aims to predict rupture risk without surgery

NCT ID NCT04578808

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study follows 1,000 people with small, unruptured brain aneurysms (3-7 mm) for three years. Researchers will use MRI scans to see if a specific imaging sign—wall enhancement—can predict which aneurysms grow. The goal is to create a safer, personalized monitoring plan so that only high-risk aneurysms get treated.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could lead to a personalized follow-up plan for people with unruptured brain aneurysms, reducing unnecessary treatments and anxiety.

What could go wrong

This is an observational study, not a treatment trial. It may not find a reliable predictor, and results may not apply to all aneurysm types or sizes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

brain aneurysm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • AP-HP La Pitié-Salpêtrière Hospital

    RECRUITING

    Paris, Paris, 75000, France

  • AP-HP Le Kremlin Bicêtre Hospital

    RECRUITING

    Paris, Paris, 75000, France

  • Amiens University Hospital

    RECRUITING

    Amiens, Somme, 80000, France

  • Angers University Hospital

    RECRUITING

    Angers, Maine et Loire, 49000, France

  • Bordeaux University Hospital

    RECRUITING

    Bordeaux, Gironde, 33000, France

  • Brest University Hospital

    RECRUITING

    Brest, Finistère, 29200, France

  • CHU Dijon

    RECRUITING

    Dijon, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • CHU de Besançon

    RECRUITING

    Besançon, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • CHU de Caen

    RECRUITING

    Caen, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • CHU de Clermont Ferrand

    RECRUITING

    Clermont-Ferrand, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • CHU de Poitiers

    RECRUITING

    Poitiers, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • CHU de Strasbourg

    RECRUITING

    Strasbourg, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • CHU de saint Etienne

    RECRUITING

    Saint-Etienne, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Clairval's Hospital

    RECRUITING

    Marseille, Bouches-du-Rhône, 13000, France

  • Creteil University Hospital

    RECRUITING

    Créteil, Val-de-Marne, 94000, France

  • Hôpital Foch

    RECRUITING

    Suresnes, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • InselHospital Bern

    NOT_YET_RECRUITING

    Bern, 3000, Switzerland

  • Limoges University Hospital

    RECRUITING

    Limoges, Haute-Vienne, 87000, France

  • Nancy University Hospital

    RECRUITING

    Nancy, Meurthe-et-Moselle, 54000, France

  • Nantes University Hospital

    RECRUITING

    Nantes, Loire-Atlantique, 44000, France

    Contact

  • Reims University Hospital

    NOT_YET_RECRUITING

    Reims, Marne, 51100, France

  • Rennes University Hospital

    RECRUITING

    Rennes, Ille-et-Vilaine, 35000, France

  • Rostchild Foundation Hospital

    RECRUITING

    Paris, Paris, 75000, France

  • Rouen University Hospital

    RECRUITING

    Rouen, Seine-Maritime, 76000, France

  • St Anne HIA

    RECRUITING

    Toulon, France

    Contact Email: •••••@•••••

  • Ste Anne's Hospital

    RECRUITING

    Paris, Île-de-France Region, 75674, France

  • Toulouse University Hospital

    RECRUITING

    Toulouse, Haute-Garonne, 31000, France

  • Tours University Hospital

    RECRUITING

    Tours, Indre-et-Loire, 37000, France

  • UMC Utrecht

    COMPLETED

    Utrecht, 3500, Netherlands