Brain aneurysm study aims to predict rupture risk without surgery
NCT ID NCT04578808
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study follows 1,000 people with small, unruptured brain aneurysms (3-7 mm) for three years. Researchers will use MRI scans to see if a specific imaging sign—wall enhancement—can predict which aneurysms grow. The goal is to create a safer, personalized monitoring plan so that only high-risk aneurysms get treated.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to a personalized follow-up plan for people with unruptured brain aneurysms, reducing unnecessary treatments and anxiety.
- What could go wrong
- This is an observational study, not a treatment trial. It may not find a reliable predictor, and results may not apply to all aneurysm types or sizes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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AP-HP La Pitié-Salpêtrière Hospital
RECRUITINGParis, Paris, 75000, France
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AP-HP Le Kremlin Bicêtre Hospital
RECRUITINGParis, Paris, 75000, France
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Amiens University Hospital
RECRUITINGAmiens, Somme, 80000, France
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Angers University Hospital
RECRUITINGAngers, Maine et Loire, 49000, France
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Bordeaux University Hospital
RECRUITINGBordeaux, Gironde, 33000, France
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Brest University Hospital
RECRUITINGBrest, Finistère, 29200, France
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CHU Dijon
RECRUITINGDijon, France
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CHU de Besançon
RECRUITINGBesançon, France
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CHU de Caen
RECRUITINGCaen, France
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CHU de Clermont Ferrand
RECRUITINGClermont-Ferrand, France
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CHU de Poitiers
RECRUITINGPoitiers, France
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CHU de Strasbourg
RECRUITINGStrasbourg, France
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CHU de saint Etienne
RECRUITINGSaint-Etienne, France
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Clairval's Hospital
RECRUITINGMarseille, Bouches-du-Rhône, 13000, France
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Creteil University Hospital
RECRUITINGCréteil, Val-de-Marne, 94000, France
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Hôpital Foch
RECRUITINGSuresnes, France
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InselHospital Bern
NOT_YET_RECRUITINGBern, 3000, Switzerland
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Limoges University Hospital
RECRUITINGLimoges, Haute-Vienne, 87000, France
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Nancy University Hospital
RECRUITINGNancy, Meurthe-et-Moselle, 54000, France
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Nantes University Hospital
RECRUITINGNantes, Loire-Atlantique, 44000, France
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Reims University Hospital
NOT_YET_RECRUITINGReims, Marne, 51100, France
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Rennes University Hospital
RECRUITINGRennes, Ille-et-Vilaine, 35000, France
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Rostchild Foundation Hospital
RECRUITINGParis, Paris, 75000, France
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Rouen University Hospital
RECRUITINGRouen, Seine-Maritime, 76000, France
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St Anne HIA
RECRUITINGToulon, France
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Ste Anne's Hospital
RECRUITINGParis, Île-de-France Region, 75674, France
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Toulouse University Hospital
RECRUITINGToulouse, Haute-Garonne, 31000, France
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Tours University Hospital
RECRUITINGTours, Indre-et-Loire, 37000, France
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UMC Utrecht
COMPLETEDUtrecht, 3500, Netherlands
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Other studies related to the condition(s) this trial covers.
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