Massive study suggests common heart drugs may shield brain from dementia

NCT ID NCT05794997

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study looked at health records from over 800,000 older adults to see if certain blood pressure drugs (propranolol or carvedilol) are linked to a lower risk of dementia compared to other similar drugs (atenolol, bisoprolol, or sotalol). The goal was to find if repurposing existing medicines could help prevent Alzheimer's disease. Because the study is based on past data analysis, it can suggest connections but cannot prove cause and effect.

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Conditions

The condition(s) this trial relates to.

hypertensive disorder Alzheimer disease prevention target dementia prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States