Can a simple drug combo make intubation safer for seniors?

NCT ID NCT07258628

Completed Symptom relief Sponsor: Ankara City Hospital Bilkent Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether giving magnesium sulfate and fentanyl before intubation (placing a breathing tube) can prevent sudden spikes in blood pressure and heart rate in patients aged 50 and older. 76 participants were split into three groups: magnesium alone, fentanyl alone, or both drugs together. The goal was to see which approach best keeps vital signs stable during this critical procedure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: magnesium sulfate and fentanyl
What this could lead to: If successful, this could lead to a simple drug combination to make intubation safer for older adults by preventing sudden blood pressure and heart rate spikes.
What could go wrong: This is a small, completed trial with only 76 participants, so results may not apply to all patients. The drugs themselves can have side effects like low blood pressure or breathing problems.

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Conditions

The condition(s) this trial relates to.

hypertensive disorder Tachycardia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HYPERTENSION TACHYCARDIA

Contacts and locations

Locations

Ankara Bilkent City Hospital, Department of Anesthesiology and Reanimation

Ankara, Ankara, 06800, Turkey (Türkiye)
Ankara City Hospital

Ankara, 06800, Turkey (Türkiye)

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