Nausea drug may unlock new hypertension treatment in diabetes

NCT ID NCT02811055

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This small pilot study looked at whether aprepitant, a drug used for nausea, can reduce aldosterone (a hormone that raises blood pressure) in people with type 2 diabetes and low-renin hypertension. Five participants took either aprepitant or a placebo for two weeks, then switched after a break. The goal was to understand how the nervous system affects hormone production in diabetes, not to prove a new treatment.

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Conditions

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As listed by the trial registrant

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Contacts and locations

Locations

  • Rouen University Hospital

    Rouen, France

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