Nausea drug may unlock new hypertension treatment in diabetes
NCT ID NCT02811055
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This small pilot study looked at whether aprepitant, a drug used for nausea, can reduce aldosterone (a hormone that raises blood pressure) in people with type 2 diabetes and low-renin hypertension. Five participants took either aprepitant or a placebo for two weeks, then switched after a break. The goal was to understand how the nervous system affects hormone production in diabetes, not to prove a new treatment.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
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The condition terms exactly as the trial's registrant entered them.
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Locations
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Rouen University Hospital
Rouen, France