Nausea drug may unlock new hypertension treatment in diabetes
NCT ID NCT02811055
First seen Jun 27, 2026 ยท Last updated Jun 27, 2026
Summary
This small pilot study looked at whether aprepitant, a drug used for nausea, can reduce aldosterone (a hormone that raises blood pressure) in people with type 2 diabetes and low-renin hypertension. Five participants took either aprepitant or a placebo for two weeks, then switched after a break. The goal was to understand how the nervous system affects hormone production in diabetes, not to prove a new treatment.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
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Contacts and locations
Locations
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Rouen University Hospital
Rouen, France
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