Massive medicare study hints at Alzheimer's prevention in blood pressure pills

NCT ID NCT05125237

First seen Nov 06, 2025 · Last updated May 18, 2026 · Updated 25 times

Summary

This study looked at medical records from over 155,000 older adults with high blood pressure to see if two common diuretics, amiloride and triamterene, affect the risk of developing dementia or Alzheimer's disease. Researchers analyzed data from Medicare claims between 2008 and 2018. The goal was to find out if one drug might be better at protecting the brain, but the study only observed existing data and did not test a new treatment.

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Contacts and locations

Locations

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02120, United States

Conditions

Explore the condition pages connected to this study.