Infectious disease
MONDO:0005550A disorder directly resulting from the presence and activity of a microbial, viral, or parasitic agent in humans. It can be transmitted by direct or indirect contact.
Also known as: communicable disease, infection, infectious, infectious disease, infectious diseases and manifestations, infectious disorder, transmissible disease, clinical infection
7066 clinical trials for this condition and its sub-types.
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Broader categories
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Sanofi's COVID vaccine trial ends early – what we know
⭐️ VACCINE ⭐️ TerminatedThis Phase 3 study tested two Sanofi COVID-19 vaccines (one targeting the original virus, another targeting two variants) in about 24,000 adults. The goal was to see if they could prevent COVID-19 safely. The trial was terminated early, so final results are limited, but the data …
Phase: PHASE3 • Sponsor: Sanofi Pasteur, a Sanofi Company • Aim: ⭐️ VACCINE ⭐️
Last updated Jun 27, 2026 13:00 UTC
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MRNA shingles vaccine trial ends early – what we know
⭐️ VACCINE ⭐️ TerminatedThis study tested several experimental mRNA vaccines against shingles in healthy adults aged 50 to 85. The goal was to check safety and immune response compared to the current shingles vaccine, Shingrix. The trial was terminated early, so results are limited, but the data may hel…
Phase: PHASE1, PHASE2 • Sponsor: Pfizer • Aim: ⭐️ VACCINE ⭐️
Last updated Jun 27, 2026 12:29 UTC
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Experimental HIV vaccine trial ends early – what we know
⭐️ VACCINE ⭐️ TerminatedThis early-stage trial tested an experimental HIV vaccine in 44 healthy adults to see if it was safe and triggered an immune response. The vaccine uses a piece of the HIV virus (fusion peptide) to train the body's defenses. The study was terminated early, so the full results are …
Phase: PHASE1 • Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: ⭐️ VACCINE ⭐️
Last updated Jun 27, 2026 12:23 UTC
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Ebola vaccine in a nasal spray? early trial halted
⭐️ VACCINE ⭐️ TerminatedThis early-stage trial tested a nasal spray vaccine against Ebola in 15 healthy adults. The vaccine uses a weakened common cold virus to deliver a piece of the Ebola virus. The study aimed to check safety and immune response, but it was terminated early, so results are limited.
Phase: PHASE1 • Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: ⭐️ VACCINE ⭐️
Last updated Jun 27, 2026 11:03 UTC
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New RSV vaccine for infants shows promise in major trial
⭐️ VACCINE ⭐️ TerminatedThis study tested an experimental RSV vaccine given to healthy infants at 6 and 12 months old alongside their regular vaccines. The goal was to see if the RSV vaccine still worked well when given at the same time. About 2,200 babies took part, but the study was stopped early.
Phase: PHASE3 • Sponsor: Sanofi Pasteur, a Sanofi Company • Aim: ⭐️ VACCINE ⭐️
Last updated Jun 27, 2026 09:01 UTC
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Could a Lower-Dose RSV vaccine protect babies just as well?
⭐️ VACCINE ⭐️ TerminatedThis study tested a nasal spray RSV vaccine in nearly 1,000 healthy infants and toddlers aged 6 to 22 months. The goal was to see if a lower dose works as well as the standard dose and to check safety across different doses. The trial was ended early, so final results are not ava…
Phase: PHASE3 • Sponsor: Sanofi Pasteur, a Sanofi Company • Aim: ⭐️ VACCINE ⭐️
Last updated Jun 27, 2026 09:01 UTC
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RSV nasal vaccine trial for kids halted – what we know
⭐️ VACCINE ⭐️ TerminatedThis phase 3 study tested an intranasal RSV vaccine in about 6,300 healthy children aged 6 to 22 months. The goal was to see if two doses of the nasal spray could prevent lower respiratory tract infections caused by RSV. The trial was terminated early, so final results are not av…
Phase: PHASE3 • Sponsor: Sanofi Pasteur, a Sanofi Company • Aim: ⭐️ VACCINE ⭐️
Last updated Jun 27, 2026 09:01 UTC
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Early malaria vaccine trial halted – what we know
⭐️ VACCINE ⭐️ TerminatedThis early-stage trial tested a new vaccine against Plasmodium vivax malaria, given with an adjuvant to boost immune response. It involved 25 healthy adults in the UK to check safety and immune reactions. The study was terminated early, so full results are not available.
Phase: EARLY_PHASE1 • Sponsor: University of Oxford • Aim: ⭐️ VACCINE ⭐️
Last updated Jun 27, 2026 08:12 UTC
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UK volunteers test new ebola vaccine combo in Early-Stage trial
⭐️ VACCINE ⭐️ TerminatedThis early-stage trial tested the safety and immune response of two experimental Ebola vaccines in 38 healthy UK adults. Some volunteers received one vaccine, while others got a prime-boost combination. The vaccines use harmless viruses to train the immune system against Ebola wi…
Phase: PHASE1 • Sponsor: University of Oxford • Aim: ⭐️ VACCINE ⭐️
Last updated Jun 27, 2026 08:05 UTC
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New mRNA vaccine aimed at preventing common but risky virus
⭐️ VACCINE ⭐️ TerminatedThis phase 3 trial tested an mRNA vaccine (mRNA-1647) to prevent cytomegalovirus (CMV) infection in healthy people aged 16 to 40. The study enrolled over 7,400 participants, focusing on women who had never been infected with CMV. The vaccine aims to trigger an immune response to …
Phase: PHASE3 • Sponsor: ModernaTX, Inc. • Aim: ⭐️ VACCINE ⭐️
Last updated Jun 27, 2026 08:04 UTC
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COVID vaccine trial for babies halted early – Here's what we know
⭐️ VACCINE ⭐️ TerminatedThis study looked at whether the mRNA-1273.214 COVID-19 vaccine is safe and works in infants as young as 12 weeks to under 6 months old. It was a small, early-stage trial that was stopped before completion. The main goal was to check for side effects like fever, fussiness, and in…
Phase: PHASE2 • Sponsor: ModernaTX, Inc. • Aim: ⭐️ VACCINE ⭐️
Last updated Jun 27, 2026 08:00 UTC
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New MenB vaccine trial aims to protect babies to adults
⭐️ VACCINE ⭐️ TerminatedThis early-stage study tested a new meningococcal B vaccine in 576 healthy people, from infants to adults. Researchers checked for side effects and measured immune responses, comparing the new vaccine to two already-approved ones. The goal was to see if the vaccine is safe and tr…
Phase: PHASE1 • Sponsor: Sanofi Pasteur, a Sanofi Company • Aim: ⭐️ VACCINE ⭐️
Last updated Jun 27, 2026 07:54 UTC
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Sanofi mRNA vaccine trial ends early – what we know
⭐️ VACCINE ⭐️ TerminatedThis study tested Sanofi's experimental mRNA vaccine against COVID-19 in 182 healthy adults aged 18 and older. The main goals were to check safety and measure the body's immune response. The trial was terminated early, so full results are not available.
Phase: PHASE1, PHASE2 • Sponsor: Sanofi Pasteur, a Sanofi Company • Aim: ⭐️ VACCINE ⭐️
Last updated Jun 26, 2026 15:56 UTC
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Could a simple pill tame RSV? new trial tests obeldesivir
Disease control TerminatedThis phase 2 study tests whether an oral antiviral pill called obeldesivir can safely shorten RSV symptoms in adults who are not hospitalized but are at higher risk for severe disease (e.g., those aged 60+ or with chronic lung conditions). Participants take the pill or a placebo,…
Phase: PHASE2 • Sponsor: Gilead Sciences • Aim: Disease control
Last updated Jul 02, 2026 00:00 UTC
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Malaria drug combo shows promise against COVID-19 in early trial
Disease control TerminatedThis phase 2 trial tests whether a combination of atovaquone (an anti-malarial) and azithromycin (an antibiotic) can clear the COVID-19 virus in infected adults. The study enrolls people at high risk for complications, such as those with moderate to severe illness. Participants r…
Phase: PHASE2 • Sponsor: HonorHealth Research Institute • Aim: Disease control
Last updated Jul 01, 2026 00:00 UTC
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Peer support may boost HIV treatment success in people who inject drugs
Disease control TerminatedThis study tests whether adding peer-based counseling to standard HIV and opioid treatment helps people who inject drugs stay on their medications and achieve viral suppression. Participants receive either enhanced usual care or extra support from a peer counselor. The goal is to…
Phase: NA • Sponsor: Yale University • Aim: Disease control
Last updated Jul 01, 2026 00:00 UTC
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Placenta cells tested as COVID fighter – but trial stopped early
Disease control TerminatedThis early-phase trial tested a new therapy called CYNK-001, which uses natural killer cells from the placenta to fight COVID-19. It enrolled only 7 adults with moderate COVID-19. The study was terminated early, so we have limited information on safety and effectiveness.
Phase: PHASE1, PHASE2 • Sponsor: Celularity Incorporated • Aim: Disease control
Last updated Jun 28, 2026 00:00 UTC
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Experimental drug aims to help COVID survivors breathe easier
Disease control TerminatedThis study tested a drug called deupirfenidone (LYT-100) in 185 adults who had breathing problems after a serious COVID-19 infection. Participants took either the drug or a placebo for several weeks to see if it improved their ability to walk. The trial was stopped early, so the …
Phase: PHASE2 • Sponsor: PureTech • Aim: Disease control
Last updated Jun 27, 2026 14:03 UTC
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Mpox drug trial halted: did tecovirimat help?
Disease control TerminatedThis study tested whether the drug tecovirimat could safely treat mpox and speed up recovery. About 719 people with mpox took either tecovirimat or a placebo. The main goals were to see if the drug reduced the time for skin lesions to heal and lessened pain. The study was termina…
Phase: PHASE3 • Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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New oral pill aims to fight RSV in adults
Disease control TerminatedThis study tests an oral drug called AK0529 (Ziresovir) in adults aged 18 to 75 with respiratory syncytial virus (RSV) infection. Participants receive either the drug or a placebo, and researchers measure how well symptoms improve and track any side effects. The goal is to see if…
Phase: PHASE2 • Sponsor: Shanghai Ark Biopharmaceutical Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 14:01 UTC
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Promising c. diff drug fails to prove benefit in small, halted trial
Disease control TerminatedThis study tested whether an extra dose of bezlotoxumab, a drug that blocks the harmful toxin made by C. diff bacteria, could help very sick patients recover after emergency colon surgery. Only 5 people took part before the study was stopped early. The goal was to see if the drug…
Phase: PHASE4 • Sponsor: Ohio State University • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Liver transplants for HIV-HCV patients: a feasibility study
Disease control TerminatedThis study aimed to see if liver transplantation is possible and safe for people infected with both HIV and hepatitis C. Fifteen patients were enrolled to track survival, virus behavior, and drug interactions after transplant. The goal was to understand how these two viruses inte…
Phase: PHASE2 • Sponsor: ANRS, Emerging Infectious Diseases • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Hepatitis b drug combo trial halted early
Disease control TerminatedThis early-stage study tested a new experimental drug called GSK3965193, alone and in combination with another drug (bepirovirsen), for people with chronic hepatitis B. The goal was to see if the combination could lower hepatitis B virus levels and possibly lead to a sustained re…
Phase: PHASE1, PHASE2 • Sponsor: GlaxoSmithKline • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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New hope for stubborn lung infection? trial of epetraborole begins, then stops
Disease control TerminatedThis study tested an oral drug called epetraborole for people with a tough-to-treat lung infection called MAC lung disease. The trial aimed to see if adding epetraborole to standard treatment could improve symptoms and clear the infection. However, the study was terminated early,…
Phase: PHASE2, PHASE3 • Sponsor: AN2 Therapeutics, Inc • Aim: Disease control
Last updated Jun 27, 2026 13:07 UTC
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Can an extra shot boost COVID protection in autoimmune patients?
Disease control TerminatedThis study tests whether an additional dose of a COVID-19 vaccine can improve immune protection in adults and children with autoimmune diseases like rheumatoid arthritis, lupus, multiple sclerosis, and others who are taking immunosuppressive medications. Participants who had a we…
Phase: PHASE2 • Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Disease control
Last updated Jun 27, 2026 13:06 UTC
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COVID-19 drug trial halted early: only 16 patients enrolled
Disease control TerminatedThis study tested an experimental drug called APX-115 in hospitalized patients with mild to moderate COVID-19. The goal was to see if it was safe and could help people recover faster. However, the trial was stopped early and only 16 people took part, so we don't have enough infor…
Phase: PHASE2 • Sponsor: Aptabio Therapeutics, Inc. • Aim: Disease control
Last updated Jun 27, 2026 13:05 UTC
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Can a smaller dose of arthritis drug tame COVID-19 lung inflammation?
Disease control TerminatedThis study tested whether a low dose of tocilizumab, a drug used for arthritis, could help hospitalized COVID-19 patients with lung inflammation who were not on a breathing machine. The goal was to see if it sped up recovery and reduced deaths. The trial was stopped early, but re…
Phase: PHASE2 • Sponsor: University of Chicago • Aim: Disease control
Last updated Jun 27, 2026 13:04 UTC
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HIV drug showdown: which strategy works best for new patients?
Disease control TerminatedThis study compared two HIV treatment approaches in people who had never taken HIV drugs before. One group started with a three-drug combo for 16 weeks, then switched to a two-drug combo. The other group took a two-drug combo from the start. The goal was to see if the first appro…
Phase: PHASE3 • Sponsor: ANRS, Emerging Infectious Diseases • Aim: Disease control
Last updated Jun 27, 2026 13:04 UTC
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Kaposi's sarcoma drug trial halted early – what we know
Disease control TerminatedThis phase II trial tested the drug everolimus in 11 people with classic or endemic Kaposi's sarcoma, a rare skin cancer linked to a virus. The goal was to see if the drug could shrink tumors after 6 months. The study was terminated early, so the full results are not available.
Phase: PHASE2 • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Disease control
Last updated Jun 27, 2026 13:03 UTC
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Heart drug fails to prove benefit for lung failure patients in early-stop trial
Disease control TerminatedThis study tested whether giving the heart medication metoprolol through a vein could help people with severe lung failure (ARDS) in the ICU. The goal was to see if it helped them breathe without a machine for more days. However, the trial was stopped early and only 14 people too…
Phase: PHASE3 • Sponsor: Consorcio Centro de Investigación Biomédica en Red (CIBER) • Aim: Disease control
Last updated Jun 27, 2026 13:02 UTC
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Could aspirin or ibuprofen help beat TB faster?
Disease control TerminatedThis study tested whether adding aspirin or ibuprofen to standard tuberculosis (TB) treatment helps patients recover more quickly. It included 426 adults with drug-sensitive or drug-resistant TB. The trial was terminated early, so the results are not conclusive.
Phase: PHASE2 • Sponsor: Fundació Institut Germans Trias i Pujol • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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HIV drug switch may boost heart health and trim body fat
Disease control TerminatedThis study looked at whether switching from a standard HIV drug combination to a different one (Delstrigo) could improve cholesterol, body fat, and blood sugar in people with HIV. The study planned to enroll 60 adults whose HIV was already well-controlled. Participants were rando…
Phase: PHASE4 • Sponsor: Chelsea and Westminster NHS Foundation Trust • Aim: Disease control
Last updated Jun 27, 2026 12:39 UTC
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Hospital hep c treatment aims to cure drug users
Disease control TerminatedThis study tested giving hepatitis C treatment to people who inject drugs while they were already in the hospital for other infections. The goal was to cure their hepatitis C and make sure they stayed connected to care afterward. The study was stopped early, but it included 21 pa…
Phase: NA • Sponsor: Kirby Institute • Aim: Disease control
Last updated Jun 27, 2026 12:37 UTC
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Experimental immune cell therapy for transplant viruses shows early promise but study halted
Disease control TerminatedThis early-stage trial tested whether specially grown immune cells could help transplant patients fight off stubborn viral infections. The study included 8 people who had received a stem cell or organ transplant and had ongoing infections with adenovirus, CMV, or EBV. The approac…
Phase: PHASE1, PHASE2 • Sponsor: Jessie L. Alexander, MD • Aim: Disease control
Last updated Jun 27, 2026 12:37 UTC
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Carbon monoxide as medicine? tiny trial tests inhaled gas for lung failure
Disease control TerminatedThis early-phase trial tested whether inhaling low doses of carbon monoxide could be safe for people with severe lung injury caused by sepsis. Only 5 participants were enrolled before the study was stopped early. The goal was to see if a personalized dosing formula could safely a…
Phase: PHASE1 • Sponsor: Brigham and Women's Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:37 UTC
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New TB drug cocktails aim to cut treatment time in half
Disease control TerminatedThis clinical trial tested whether combining several drugs—bedaquiline, OPC-167832, sutezolid, and either pretomanid or delamanid—could treat pulmonary tuberculosis in just 2 to 4 months instead of the standard 6 months. The study enrolled 93 adults with drug-sensitive or drug-re…
Phase: PHASE2 • Sponsor: Gates Medical Research Institute • Aim: Disease control
Last updated Jun 27, 2026 12:35 UTC
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Experimental drug INB03 tested to stop COVID-19 lung decline – trial halted early
Disease control TerminatedThis study tested a drug called INB03 in 79 high-risk COVID-19 patients to see if it could prevent their breathing from getting worse. Participants received two weekly injections of either INB03 or a placebo. The trial was terminated early, so we do not have clear results on whet…
Phase: PHASE2, PHASE3 • Sponsor: Inmune Bio, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:35 UTC
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Plasma from recovered patients tested against COVID-19 – trial ends early
Disease control TerminatedThis study tested whether giving plasma (the liquid part of blood) from people who recovered from COVID-19 could help hospitalized patients with moderate to severe COVID-19. The plasma contains antibodies that might fight the virus. The trial planned to enroll many patients but w…
Phase: PHASE3 • Sponsor: South African National Blood Service • Aim: Disease control
Last updated Jun 27, 2026 12:31 UTC
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Shorter antibiotic course after heart surgery for IV drug users shows promise
Disease control TerminatedThis study looked at whether people who had heart surgery for endocarditis (a serious heart infection) related to IV drug use could safely switch from IV antibiotics to oral pills after just two weeks. The goal was to see if this shorter hospital stay was safe and effective. The …
Phase: PHASE4 • Sponsor: West Virginia University • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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Tonsil infection showdown: surgery vs. drainage
Disease control TerminatedThis study looked at the best way to treat a tonsillar abscess, a painful infection near the tonsils. It compared two treatments: removing the tonsils (tonsillectomy) versus draining the pus with a needle under local anesthesia. The goal was to see which method works better to cl…
Phase: NA • Sponsor: University Hospital, Geneva • Aim: Disease control
Last updated Jun 27, 2026 12:28 UTC
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Stool test could replace endoscopy for h. pylori treatment decisions
Disease control TerminatedThis study tested whether a simple stool test can guide doctors in choosing the right antibiotics for H. pylori infections, avoiding the need for an invasive stomach camera procedure. The test detects the bacteria and checks for antibiotic resistance, aiming to improve cure rates…
Phase: NA • Sponsor: Poitiers University Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:26 UTC
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Promising fungal infection treatment study halted early
Disease control TerminatedThis study tested whether adding an inhaled medication (PC945) to standard antifungal drugs could help people with a severe, hard-to-treat lung fungal infection called invasive pulmonary aspergillosis. The trial aimed to see if the combination improved survival and response by da…
Phase: PHASE3 • Sponsor: Pulmocide Ltd • Aim: Disease control
Last updated Jun 27, 2026 12:25 UTC
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Heart drug tested to fight COVID-19 complications
Disease control TerminatedThis study tested a drug called CardiolRx in 90 hospitalized COVID-19 patients who also had heart disease or risk factors like diabetes or high blood pressure. The goal was to see if the drug could lower the chance of death, needing intensive care, or having heart problems. The t…
Phase: PHASE2, PHASE3 • Sponsor: Cardiol Therapeutics Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Weekly HIV pill shows promise but study halted early
Disease control TerminatedThis study tested whether a once-weekly oral combination of two experimental drugs (lepetegravir and lenacapavir pacfosacil) could control HIV as well as the standard daily pill Biktarvy. It enrolled 73 people newly diagnosed with HIV-1 who had never taken HIV medication. The stu…
Phase: PHASE2, PHASE3 • Sponsor: Gilead Sciences • Aim: Disease control
Last updated Jun 27, 2026 12:07 UTC
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Can cuddling save tiny babies? trial tests early kangaroo care
Disease control TerminatedThis study looked at whether starting continuous skin-to-skin contact (kangaroo mother care) within 24 hours of birth helps unstable preterm babies under 2000g survive. It compared this to standard incubator care. The trial took place in The Gambia and enrolled 279 babies, but wa…
Phase: NA • Sponsor: London School of Hygiene and Tropical Medicine • Aim: Disease control
Last updated Jun 27, 2026 12:07 UTC
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Hormone therapy and HIV drugs: a delicate balance for transgender women
Disease control TerminatedThis study looked at how feminizing hormone therapy (estradiol) interacts with HIV medications in transgender women living with HIV. It included 93 participants who were already on HIV treatment and gave them standardized estradiol doses for up to 48 weeks. The goal was to see if…
Phase: PHASE2 • Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Disease control
Last updated Jun 27, 2026 12:05 UTC
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HIV and opioid treatment study halted early – what we know
Disease control TerminatedThis study looked at whether different medications for opioid use disorder (methadone, buprenorphine/naloxone, or naltrexone) could reduce immune system inflammation in people with HIV. Researchers measured changes in blood markers of immune activation over 24 weeks. The trial wa…
Phase: PHASE2 • Sponsor: University of Pennsylvania • Aim: Disease control
Last updated Jun 27, 2026 12:04 UTC
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Hepatitis b drug combo tested in phase 3 trial – but study stopped early
Disease control TerminatedThis study tested two antiviral drugs, clevudine and tenofovir, alone or together, in 150 adults with chronic hepatitis B who had not been treated before. The goal was to see which approach worked best at controlling the virus after 96 weeks of treatment and 24 weeks of follow-up…
Phase: PHASE3 • Sponsor: French National Agency for Research on AIDS and Viral Hepatitis • Aim: Disease control
Last updated Jun 27, 2026 12:04 UTC
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Cold plasma zaps away Kids' skin lesions in new trial
Disease control TerminatedThis study tested a cold atmospheric plasma device on children aged 4-21 with warts or molluscum lesions. The device uses ionized gas to treat the lesions without heat. The trial was terminated early, so we don't have full results on how well it worked or its safety.
Phase: PHASE3 • Sponsor: Medical University of South Carolina • Aim: Disease control
Last updated Jun 27, 2026 12:04 UTC
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HIV pill combo fails to slim belly fat in early trial
Disease control TerminatedThis study tested whether switching to a two-drug HIV treatment (raltegravir plus maraviroc) could reduce belly fat (lipohypertrophy) in people whose HIV was already well-controlled. It included 48 adults on stable HIV therapy for at least 5 years. The study was stopped early, so…
Phase: PHASE2 • Sponsor: ANRS, Emerging Infectious Diseases • Aim: Disease control
Last updated Jun 27, 2026 12:04 UTC
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Cancer drug lenalidomide tested for HIV-Linked kaposi sarcoma
Disease control TerminatedThis phase 2 trial tested the drug lenalidomide in 12 people with HIV who had Kaposi sarcoma, a type of cancer. Participants took lenalidomide pills for 21 days each month. The study aimed to see if the drug could shrink tumors, but it was stopped early, so the results are not co…
Phase: PHASE2 • Sponsor: French National Agency for Research on AIDS and Viral Hepatitis • Aim: Disease control
Last updated Jun 27, 2026 12:03 UTC
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Cancer drug tested against COVID-19 in small trial
Disease control TerminatedThis study tested whether imatinib, a drug used for certain cancers, could help hospitalized adults with COVID-19. Participants received either imatinib or a placebo alongside standard care. The trial was stopped early and only included 21 people, so no firm conclusions can be dr…
Phase: PHASE3 • Sponsor: University of Maryland, Baltimore • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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Could a simple gas stop COVID-19 from getting worse?
Disease control TerminatedThis study tested whether breathing in nitric oxide gas could keep mild-to-moderate COVID-19 from becoming severe. Researchers enrolled 62 hospitalized adults who were breathing on their own. The goal was to see if the gas reduced the need for a breathing tube. The trial was stop…
Phase: PHASE2 • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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Experimental drug auxora tested in critical COVID-19 lung patients
Disease control TerminatedThis small Phase 2 trial tested an experimental drug called Auxora in 10 patients with critical COVID-19 pneumonia who were on ventilators. The goal was to see how the drug affected immune cells in the lungs and to check its safety. The study was terminated early, so results are …
Phase: PHASE2 • Sponsor: CalciMedica, Inc. • Aim: Disease control
Last updated Jun 27, 2026 11:03 UTC
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New hope for lung scarring? trial of GSK3915393 cut short
Disease control TerminatedThis study tested a new medicine, GSK3915393, in 158 people with idiopathic pulmonary fibrosis (IPF), a chronic lung disease that causes scarring and breathing difficulty. The goal was to see if the drug could slow lung function decline compared to a placebo. The trial was termin…
Phase: PHASE2 • Sponsor: GlaxoSmithKline • Aim: Disease control
Last updated Jun 27, 2026 11:01 UTC
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Experimental donor CAR-T therapy tested in lymphoma – trial halted early
Disease control TerminatedThis early-phase trial tested a new therapy called ATA3219, which uses immune cells from a healthy donor to attack cancer cells in people with relapsed or refractory B-cell non-Hodgkin lymphoma. The study aimed to check safety and see if the treatment works, but it was stopped ea…
Phase: PHASE1 • Sponsor: Atara Biotherapeutics • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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Eye infection breakthrough: new trial tests antivirals to save sight
Disease control TerminatedThis study compared two antiviral medicines (oral valganciclovir and topical ganciclovir 2%) against a placebo for treating CMV-related inflammation in the front of the eye. The goal was to see which approach better controls the infection and reduces complications like pain, glau…
Phase: PHASE2, PHASE3 • Sponsor: University of California, San Francisco • Aim: Disease control
Last updated Jun 27, 2026 09:11 UTC
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Can a simple urine test prevent kidney failure in sepsis?
Disease control TerminatedThis study tested whether using a urine biomarker test (NephroCheck) to guide treatment could reduce kidney injury, dialysis, or death in sepsis patients. The trial planned to enroll many participants but was stopped early after only 19 people joined. The idea was to catch kidney…
Phase: NA • Sponsor: BioMérieux • Aim: Disease control
Last updated Jun 27, 2026 09:11 UTC
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Could a nausea drug help fight COVID-19? early trial cut short
Disease control TerminatedThis phase 2 trial tested whether adding aprepitant, a drug usually used for nausea, to standard care could help hospitalized COVID-19 patients recover faster. The study planned to enroll adults recently admitted to the hospital with COVID-19 and signs of lung involvement. Howeve…
Phase: PHASE2 • Sponsor: Heron Therapeutics • Aim: Disease control
Last updated Jun 27, 2026 09:09 UTC
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New syphilis combo treatment tested in HIV patients – trial cut short
Disease control TerminatedThis study looked at two different antibiotic combinations for treating early syphilis in people living with HIV. One group received a single shot of ceftriaxone plus a week of doxycycline pills, while the other got the standard single shot of penicillin plus the same doxycycline…
Phase: PHASE4 • Sponsor: National Taiwan University Hospital • Aim: Disease control
Last updated Jun 27, 2026 09:08 UTC
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Experimental lymphoma drug ASTX660 tested in tiny, terminated trial
Disease control TerminatedThis early-phase trial tested the drug ASTX660 in just 8 people with T-cell lymphoma that had returned or not responded to prior treatments. The study aimed to find a safe dose and check for side effects, but it was stopped early. Because it was so small and incomplete, we cannot…
Phase: PHASE1, PHASE2 • Sponsor: Otsuka Pharmaceutical Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 09:08 UTC
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Hiprex trial for recurrent UTIs halted early – little data to go on
Disease control TerminatedThis study aimed to see if Hiprex (methenamine hippurate) could reduce recurrent urinary tract infections in women aged 50 to 85. Participants took Hiprex daily for a year, and researchers counted infections and antibiotic use. However, the trial was terminated early with only 14…
Phase: PHASE4 • Sponsor: University of Texas Southwestern Medical Center • Aim: Disease control
Last updated Jun 27, 2026 09:07 UTC
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New drug fails to show benefit in severe COVID-19 pneumonia trial
Disease control TerminatedThis study tested whether adding reparixin to standard care could prevent death or the need for a breathing machine in 414 hospitalized adults with COVID-19 or other pneumonia. The trial was stopped early. Researchers compared reparixin to a placebo to see if it reduced severe ou…
Phase: PHASE3 • Sponsor: Dompé Farmaceutici S.p.A • Aim: Disease control
Last updated Jun 27, 2026 09:07 UTC
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New vaccine aims to tame hepatitis b in patients on antivirals
Disease control TerminatedThis study tested a new therapeutic vaccine (GSK3528869A) in adults aged 18-65 with chronic hepatitis B whose virus was already well-controlled by standard antiviral pills. The goal was to see if the vaccine could safely lower hepatitis B surface antigen levels and possibly allow…
Phase: PHASE1, PHASE2 • Sponsor: GlaxoSmithKline • Aim: Disease control
Last updated Jun 27, 2026 09:07 UTC
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Can texts and peers help trans women beat HIV? trial cut short
Disease control TerminatedThis study aimed to find the best way to help transgender women living with HIV reach undetectable viral levels. Participants received either text messages, help from a peer health navigator, or both. The trial was ended early, so results are limited.
Phase: NA • Sponsor: Friends Research Institute, Inc. • Aim: Disease control
Last updated Jun 27, 2026 09:04 UTC
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Can an arthritis drug tame severe COVID-19?
Disease control TerminatedThis study tested the drug tocilizumab (Actemra) in hospitalized adults with severe COVID-19 and signs of inflammation. Participants received either the drug or a placebo, with the goal of improving clinical status by day 28. The trial was terminated early after enrolling only 20…
Phase: PHASE3 • Sponsor: Queen's Medical Center • Aim: Disease control
Last updated Jun 27, 2026 09:03 UTC
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Timing of dialysis in septic shock: early vs. delayed – study halted early
Disease control TerminatedThis study looked at 500 adults with septic shock and severe acute kidney injury to see if starting dialysis early (within 12 hours) or waiting (48-60 hours) affected survival at 90 days. The trial was terminated early, so the results are not conclusive. The goal was to find the …
Phase: PHASE3 • Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Disease control
Last updated Jun 27, 2026 09:03 UTC
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Experimental drug vixarelimab tested for two scarring lung diseases
Disease control TerminatedThis study tested the drug vixarelimab against a placebo in people with idiopathic pulmonary fibrosis (IPF) or systemic sclerosis-associated interstitial lung disease (SSc-ILD). The goal was to see if it could preserve lung function over 52 weeks. The trial was terminated early, …
Phase: PHASE2 • Sponsor: Genentech, Inc. • Aim: Disease control
Last updated Jun 27, 2026 09:03 UTC
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Hydroxychloroquine COVID trial fizzles: only 17 patients enrolled
Disease control TerminatedThis study tested whether hydroxychloroquine (a malaria drug) could help hospitalized COVID-19 patients recover faster. It planned to enroll 350 people but was stopped early with just 17 participants. Because it ended so early, we cannot say whether the drug works or is safe for …
Phase: PHASE3 • Sponsor: Queen's Medical Center • Aim: Disease control
Last updated Jun 27, 2026 09:02 UTC
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Could a common sedative save lives in septic shock?
Disease control TerminatedThis study tested whether a sedative drug called dexmedetomidine could help restore blood pressure control in patients with severe septic shock that does not respond to standard treatments. The trial involved 32 adults in intensive care. The goal was to see if the drug could impr…
Phase: PHASE3 • Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Disease control
Last updated Jun 27, 2026 09:01 UTC
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Common diabetes and acne drugs studied for head and neck cancer treatment
Disease control TerminatedThis study tested whether metformin (a diabetes drug) and doxycycline (an antibiotic) could help treat head and neck cancer when taken before surgery. The trial aimed to see if these drugs could change certain proteins in the tumor's supportive tissue. Only 7 people took part bef…
Phase: PHASE2 • Sponsor: Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
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COVID-19 drug trial halted early: what happened with ensovibep?
Disease control TerminatedThis study tested a single dose of ensovibep, a lab-made protein, in 407 adults with mild COVID-19 symptoms. The goal was to see if it could lower the amount of virus in the body and reduce hospitalizations. The trial was stopped early, so we don't have complete answers on how we…
Phase: PHASE2, PHASE3 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
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Can a probiotic pill stop UTIs from coming back?
Disease control TerminatedThis study tested a daily probiotic supplement containing Lactobacillus plantarum, cranberry, and vitamin C to see if it could prevent recurrent urinary tract infections (UTIs) in women. The trial planned to enroll 106 women with a history of frequent UTIs, but it was terminated …
Phase: NA • Sponsor: AB Biotics, SA • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
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COVID-19 drug trial halted after just 4 patients
Disease control TerminatedThis study tested whether a medicine called emetine could help adults aged 30 and older recover from COVID-19. Participants took emetine or a placebo daily for 10 days. The trial was stopped early after only 4 people enrolled, so we don't have enough information to know if emetin…
Phase: PHASE2, PHASE3 • Sponsor: Johns Hopkins University • Aim: Disease control
Last updated Jun 27, 2026 08:13 UTC
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Hepatitis b drug trial halted after early safety check
Disease control TerminatedThis early-stage study tested a new medicine called RO7565020 in healthy volunteers and people with chronic hepatitis B. The goal was to see if the drug is safe and how the body processes it. The trial was stopped early, so results are limited.
Phase: PHASE1 • Sponsor: Hoffmann-La Roche • Aim: Disease control
Last updated Jun 27, 2026 08:13 UTC
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HIV cancer hope: immune combo shows early promise but trial halted
Disease control TerminatedThis early-phase trial tested two immunotherapy drugs, ipilimumab and nivolumab, in people with HIV who had advanced solid tumors or Hodgkin lymphoma that had spread or come back. The goal was to find the safest dose and see if the combination could shrink tumors. The study was t…
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 08:13 UTC
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Rapid test plus targeted antibiotic shows promise for tough infections in blood cancer patients
Disease control TerminatedThis study tested whether the antibiotic ceftolozane-tazobactam, guided by a rapid molecular test, could effectively treat serious Pseudomonas aeruginosa infections in people with blood cancers or those who had a stem cell transplant. The 17 participants received the antibiotic t…
Phase: PHASE4 • Sponsor: Weill Medical College of Cornell University • Aim: Disease control
Last updated Jun 27, 2026 08:12 UTC
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Experimental hepatitis b drug shows promise in early trial
Disease control TerminatedThis Phase 2 trial tested an experimental drug called ARC-520 in 58 people with chronic hepatitis B who were already taking standard antivirals. The goal was to see if ARC-520 could further lower hepatitis B surface antigen levels, a marker of the virus. The study was terminated …
Phase: PHASE2 • Sponsor: Arrowhead Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC
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Experimental hepatitis b drug shows promise in early trial
Disease control TerminatedThis study tested a new drug called ARC-520 in 79 people with chronic hepatitis B. Some participants received ARC-520 alone, while others got it combined with standard treatments like entecavir or tenofovir. The goal was to see if ARC-520 could lower hepatitis B surface antigen l…
Phase: PHASE2 • Sponsor: Arrowhead Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC
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Hepatitis b drug trial halted early after safety check
Disease control TerminatedThis early-stage study tested an experimental drug called ARC-521 in healthy volunteers and people with chronic hepatitis B. The main goal was to check safety and how the body processes the drug. The study was terminated early, so results are limited.
Phase: PHASE1 • Sponsor: Arrowhead Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC
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Lung fibrosis drug study halted early
Disease control TerminatedThis study tested new single treatments for idiopathic pulmonary fibrosis (IPF), a lung disease that causes scarring and makes breathing hard. It included 46 adults aged 40 and older with mild to moderate IPF. The main goal was to see if the treatments improved lung function, mea…
Phase: PHASE2 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC
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Experimental hepatitis b drug combo shows promise but study halted early
Disease control TerminatedThis study tested an experimental drug called ARC-520 given alongside standard hepatitis B medications (entecavir or tenofovir) in 12 people with chronic hepatitis B. Participants received 9 doses of ARC-520 over 36 weeks to see if it could safely lower hepatitis B virus levels. …
Phase: PHASE2 • Sponsor: Arrowhead Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC
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Experimental hepatitis b drug shows promise in early trial
Disease control TerminatedThis study tested whether a new drug called ARC-520, given with the standard medicine entecavir, could lower hepatitis B virus levels in people with chronic hepatitis B. About 58 adults with different stages of infection received either ARC-520 or a placebo. The study was stopped…
Phase: PHASE2 • Sponsor: Arrowhead Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC
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Experimental hepatitis b drug trial halted midway
Disease control TerminatedThis study tested an experimental drug called ARC-520 in 32 adults with chronic hepatitis B who were already taking antiviral medications (entecavir or tenofovir). The goal was to see if adding ARC-520 could lower hepatitis B surface antigen levels more than placebo. The trial wa…
Phase: PHASE2 • Sponsor: Arrowhead Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC
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Cancer Patients' COVID-19 trial halted after just 4 volunteers
Disease control TerminatedThis early-phase study aimed to see if combining two immune-stimulating drugs (rintatolimod and interferon alpha-2b) could help cancer patients fight off COVID-19. Only 4 people took part before the study was stopped early. The main goals were to check safety and measure how the …
Phase: PHASE1, PHASE2 • Sponsor: Roswell Park Cancer Institute • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC
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New malaria pill for tiny infants studied, but trial stopped early
Disease control TerminatedThis study tested a new, easy-to-dissolve malaria tablet in infants and newborns weighing less than 5 kg who had uncomplicated malaria. The goal was to see how the medicine worked in the body, how safe it was, and how well it treated the infection. The trial was stopped early aft…
Phase: PHASE2, PHASE3 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC
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Experimental drug aims to keep viral pneumonia patients out of hospital
Disease control TerminatedThis Phase 2 trial tested the drug silmitasertib (CX-4945) plus standard care in adults with pneumonia caused by COVID-19 or influenza. The goal was to see if the drug could reduce the need for hospitalization or prevent death. The study planned to enroll 120 people but was termi…
Phase: PHASE2 • Sponsor: Senhwa Biosciences, Inc. • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
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Light therapy for stubborn eyelid lumps? tiny trial ends early
Disease control TerminatedThis study tested whether intense pulsed light (IPL) can help treat chalazion, a common eyelid lump. Only 4 adults with a fresh chalazion were enrolled, and the trial was stopped early. Because of the very small size, we cannot say if IPL works or is safe for this condition.
Phase: NA • Sponsor: Lumenis Be Ltd. • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
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Early antibiotics in ICU aspiration: small trial halted before answers
Disease control TerminatedThis study tested whether giving antibiotics early to ICU patients who may have inhaled stomach contents could prevent pneumonia and improve recovery. Only 5 patients were enrolled before the trial was stopped early. The results are too limited to draw any conclusions about wheth…
Phase: PHASE4 • Sponsor: UConn Health • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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New RSV drug tested in kids – but trial halted early
Disease control TerminatedThis study tested the safety and dosing of sisunatovir, an experimental antiviral drug, in infants and children up to 5 years old with RSV lower respiratory tract infection. Ten participants received either the drug or a placebo. The goal was to find the right dose for future stu…
Phase: PHASE1 • Sponsor: Pfizer • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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MRSA decolonization kit trial stalls after just one patient
Disease control TerminatedThis study tested a complete kit using povidone-iodine (Betadine) gel, soap, and mouthwash to clear MRSA bacteria from patients' noses, skin, and mouths. The goal was to see if the kit could quickly decolonize MRSA within 6 hours. However, the trial was terminated early after enr…
Phase: PHASE2 • Sponsor: Nantes University Hospital • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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New pill could fight dangerous fungal infections
Disease control TerminatedThis study tested a new oral antifungal drug, ibrexafungerp, for treating serious Candida infections in the blood or internal organs. 68 adults received an IV antifungal followed by either ibrexafungerp or standard oral fluconazole. The trial was stopped early, so the results are…
Phase: PHASE3 • Sponsor: Scynexis, Inc. • Aim: Disease control
Last updated Jun 27, 2026 08:05 UTC
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COVID drug trial for kids halted early
Disease control TerminatedThis study tested the drug baricitinib in children aged 1 to 18 who were hospitalized with COVID-19 and needed extra oxygen. The goal was to see if the drug was safe and how it worked in kids. Only 6 children took part before the study was stopped early.
Phase: PHASE3 • Sponsor: Eli Lilly and Company • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
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New hope for recurring c. diff: which treatment works best?
Disease control TerminatedThis study tested three different antibiotic regimens for people with recurrent Clostridium difficile infection (C. diff), a serious gut infection that keeps coming back. The goal was to see if newer drugs like fidaxomicin or a tapered/pulsed course of vancomycin work better than…
Phase: PHASE4 • Sponsor: VA Office of Research and Development • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
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Can an antiviral drug help sepsis patients breathe on their own sooner?
Disease control TerminatedThis phase 3 trial tested whether the antiviral drug ganciclovir could prevent reactivation of cytomegalovirus (CMV) in adults with sepsis who needed a breathing machine. The study enrolled 205 CMV-positive patients in the ICU with acute respiratory failure. Participants received…
Phase: PHASE3 • Sponsor: Fred Hutchinson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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Radioactive seeds zapped tumors from the inside — but trial stopped early
Disease control TerminatedThis early study tested a device that places radioactive seeds directly into skin, mouth, or soft tissue tumors. The seeds release alpha radiation to kill cancer cells from within. Only 2 people took part before the trial was stopped, so we don't have enough information to know i…
Phase: NA • Sponsor: Alpha Tau Medical LTD. • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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HepTcell hepatitis b vaccine trial ends early: what it means
Disease control TerminatedThis study tested a treatment called HepTcell, which is like a vaccine that trains the immune system to fight the hepatitis B virus. It was for people with inactive chronic hepatitis B who had not received treatment before. The goal was to see if it could lower virus levels or cl…
Phase: PHASE2 • Sponsor: Altimmune, Inc. • Aim: Disease control
Last updated Jun 27, 2026 08:02 UTC
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Polio Survivors' hope dashed: trial of immune treatment halted early
Disease control TerminatedThis study tested a blood product called immune globulin (Flebogamma) in 191 people with post-polio syndrome, a condition causing new muscle weakness years after polio. The goal was to see if it could improve walking distance and reduce pain. The trial was terminated early, so we…
Phase: PHASE2, PHASE3 • Sponsor: Instituto Grifols, S.A. • Aim: Disease control
Last updated Jun 27, 2026 08:02 UTC
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Promising IPF drug trial halted midway
Disease control TerminatedThis study tested an experimental drug called HZN-825 in people with idiopathic pulmonary fibrosis (IPF), a lung disease that causes scarring and makes breathing hard. The trial aimed to see if the drug could slow the decline in lung function over a year. About 153 adults with IP…
Phase: PHASE2 • Sponsor: Amgen • Aim: Disease control
Last updated Jun 27, 2026 08:01 UTC
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Quick test could spare kids from strong antibiotics for UTIs
Disease control TerminatedThis study tested whether a rapid lab test (looking for integrons in urine) could help doctors choose a narrow-spectrum antibiotic instead of a broad-spectrum one for children with fever and a urinary tract infection. The goal was to see if this approach works as well as standard…
Phase: NA • Sponsor: University Hospital, Limoges • Aim: Disease control
Last updated Jun 27, 2026 08:00 UTC
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Experimental COVID-19 drug fails to prevent respiratory failure in High-Risk patients
Disease control TerminatedThis study tested an experimental drug called ABX464 in 509 high-risk COVID-19 patients aged 65 and older, or those 18+ with risk factors like obesity or diabetes. The goal was to see if the drug could reduce inflammation and prevent the need for high-flow oxygen or a breathing m…
Phase: PHASE2, PHASE3 • Sponsor: Abivax S.A. • Aim: Disease control
Last updated Jun 27, 2026 08:00 UTC
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Cancer-Fighting virus injected directly into tumors shows promise in early trial
Disease control TerminatedThis early-phase trial tested a new treatment called BT-001, a virus designed to infect and kill cancer cells, given alone or with the immunotherapy drug pembrolizumab. The study involved 31 people with advanced solid tumors like melanoma, lung cancer, or sarcoma that had spread.…
Phase: PHASE1, PHASE2 • Sponsor: Transgene • Aim: Disease control
Last updated Jun 27, 2026 07:58 UTC
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COVID pill trial halted early: what happened?
Disease control TerminatedThis study tested an oral antiviral drug called ensitrelvir in hospitalized COVID-19 patients. The goal was to see if it could help them recover faster. However, the trial was stopped early, so we have limited information on whether it works.
Phase: PHASE3 • Sponsor: University of Minnesota • Aim: Disease control
Last updated Jun 27, 2026 07:57 UTC
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Promising c. diff drug trial halted after just 3 patients
Disease control TerminatedThis study tested a new drug called REC-3964 to see if it could prevent repeat Clostridioides difficile (C. diff) infections in adults. Only 3 people were enrolled before the trial was stopped early. The goal was to check safety and whether the drug helped people stay infection-f…
Phase: PHASE2 • Sponsor: Recursion Pharmaceuticals Inc. • Aim: Disease control
Last updated Jun 27, 2026 07:57 UTC
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Experimental HIV therapy aims to free patients from daily pills
Disease control TerminatedThis early-stage trial tests two experimental vaccines, HB-502 and HB-501, designed to teach the immune system to recognize and attack HIV. The study includes 30 people with HIV who are already on suppressive antiretroviral therapy. Participants receive injections every 8 weeks f…
Phase: PHASE1 • Sponsor: Hookipa Biotech GmbH • Aim: Disease control
Last updated Jun 27, 2026 07:57 UTC
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COVID-19 drug trial halted: LAU-7b studied in hospitalized patients
Disease control TerminatedThis study tested an experimental drug called LAU-7b in adults hospitalized with COVID-19 who had health issues like diabetes that put them at higher risk for complications. The goal was to see if LAU-7b could prevent respiratory failure or the need for a breathing machine. The t…
Phase: PHASE2, PHASE3 • Sponsor: Laurent Pharmaceuticals Inc. • Aim: Disease control
Last updated Jun 27, 2026 07:57 UTC
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New inhaled drug aimed at stubborn lung infection shows promise, but trial halted early
Disease control TerminatedThis phase 3 study tested an inhaled form of the antibiotic clofazimine added to standard therapy for people with MAC lung disease that did not respond to previous treatment. The goal was to see if the drug could clear the infection from sputum cultures and improve quality of lif…
Phase: PHASE3 • Sponsor: Mannkind Corporation • Aim: Disease control
Last updated Jun 27, 2026 07:57 UTC
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HIV drug extension study halted early: what happened?
Disease control TerminatedThis study looked at whether weekly injections of PRO 140, taken with standard HIV medications, could keep the virus under control over the long term. It enrolled 43 people who had already completed an earlier PRO 140 study and had undetectable virus levels. The study was termina…
Phase: PHASE2, PHASE3 • Sponsor: CytoDyn, Inc. • Aim: Disease control
Last updated Jun 27, 2026 07:57 UTC
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RSV pill study halted early: what we know
Disease control TerminatedThis study tested an oral drug called sisunatovir for treating RSV in adults who were not hospitalized but had a high risk of severe illness. Participants took either the drug or a placebo for 5 days. The study was terminated early, so results are limited.
Phase: PHASE2, PHASE3 • Sponsor: Pfizer • Aim: Disease control
Last updated Jun 27, 2026 07:56 UTC
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Promising combo for tough blood cancers halted early — only 4 patients enrolled
Disease control TerminatedThis study tested whether adding rapamycin to high-dose chemotherapy could help people with aggressive blood cancers (like certain leukemias and lymphomas) that had returned or not responded to prior treatment. Only 4 adults aged 18–65 took part before the study was stopped early…
Phase: PHASE1, PHASE2 • Sponsor: Abramson Cancer Center at Penn Medicine • Aim: Disease control
Last updated Jun 27, 2026 07:56 UTC
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Experimental hepatitis b drug trial halted early
Disease control TerminatedThis study tested an experimental drug called ARC-520 in people with chronic hepatitis B who were already taking standard antiviral medications. The goal was to see if ARC-520 could further lower hepatitis B surface antigen levels. Only 4 people enrolled before the study was stop…
Phase: PHASE2 • Sponsor: Arrowhead Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 07:56 UTC
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HIV patients test weekly shots to replace daily pills
Disease control TerminatedThis study tested whether HIV patients who already had the virus under control could switch to weekly injections of leronlimab (PRO 140) instead of their usual daily pills. The goal was to see if the drug alone could keep the virus suppressed safely over a longer period. The tria…
Phase: PHASE2, PHASE3 • Sponsor: CytoDyn, Inc. • Aim: Disease control
Last updated Jun 27, 2026 07:56 UTC
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COVID-19 antibody drug trial halted early — little data to show
Disease control TerminatedThis early-stage study tested a new antibody drug (REGN14256) alone or with imdevimab in 25 adults with mild COVID-19 and no risk factors for severe illness. The goal was to check safety and whether the drug could lower virus levels. However, the trial was terminated early, so we…
Phase: PHASE1, PHASE2 • Sponsor: Regeneron Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
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Experimental cell therapy targets deadly childhood brain cancer
Disease control TerminatedThis early-phase trial tested a new immunotherapy approach for children with DIPG, a rare and aggressive brain stem tumor. After standard radiation and chemotherapy, patients received special vaccines and immune cells designed to attack the tumor. The study was small (11 particip…
Phase: PHASE1 • Sponsor: University of Florida • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
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Can a drug combo let HIV patients ditch daily meds?
Disease control TerminatedThis study tested two experimental drugs, budigalimab and ABBV-382, in people with HIV who were stable on standard therapy. Participants stopped their usual HIV medications to see if the new drugs could keep the virus under control. The trial was terminated early, so it's unclear…
Phase: PHASE2 • Sponsor: AbbVie • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
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COVID antibody drug trial halted: hope for severe cases unfulfilled
Disease control TerminatedThis study tested a lab-made antibody called SCTA01 in adults hospitalized with severe COVID-19. The goal was to see if it could help them recover faster. The trial was stopped early, so we don't have clear results on its effectiveness.
Phase: PHASE2, PHASE3 • Sponsor: Sinocelltech Ltd. • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
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New HIV drug candidate GS-1219 tested in tiny early trial
Disease control TerminatedThis was a small, early-phase study testing an experimental HIV drug called GS-1219 in just 4 people living with HIV-1. The goal was to check the drug's safety and how well it fights the virus. The study was terminated early, so results are very limited.
Phase: PHASE1 • Sponsor: Gilead Sciences • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
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New program aims to boost HIV medication adherence for medicaid patients
Disease control TerminatedThis study tested a program to help Virginia Medicaid enrollees with HIV fill their antiretroviral prescriptions on time. The program offered support from providers, pharmacies, and community groups, with extra help for those who were very late refilling. Only 4 people enrolled b…
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
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New HIV drug trial halted early – what happened?
Disease control TerminatedThis study tested an experimental HIV drug called VH3739937 in 21 adults with HIV who had never taken HIV medication before. The goal was to see how well the drug lowered the virus level in the blood over a short time. The trial was stopped early, and results are limited.
Phase: PHASE2 • Sponsor: ViiV Healthcare • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
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COVID antibody study for vulnerable kids halted early
Disease control TerminatedThis study tested a single injection of two lab-made antibodies (casirivimab and imdevimab) in children under 12 who are at high risk for severe COVID-19. The goal was to see how the drug behaves in the body, if it is safe, and if it triggers an immune response. Only 7 children t…
Phase: PHASE2 • Sponsor: Regeneron Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
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COVID antibody drug tested in kids – but study stopped early
Disease control TerminatedThis study tested a single dose of casirivimab+imdevimab (REGN-COV2) in children hospitalized with COVID-19. The goal was to see how the drug behaves in the body and whether it is safe. However, the study was terminated early and only enrolled 2 participants, so we have very litt…
Phase: PHASE1 • Sponsor: Regeneron Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 07:54 UTC
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HIV Antibody-Only therapy falls short in Long-Term trial
Disease control TerminatedThis study tested whether a single antibody called PRO 140 could keep HIV under control in 20 adults who had been stable on standard combination therapy. Participants stopped their usual HIV pills and received only PRO 140 infusions. The trial was stopped early, and the main goal…
Phase: PHASE2 • Sponsor: CytoDyn, Inc. • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC
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New antibody treatment aims to shield transplant patients from dangerous virus
Disease control TerminatedThis study tested a drug called Cytotect, which contains antibodies against the CMV virus, to prevent CMV infection in people who had a stem cell transplant and developed graft-versus-host disease (GVHD). These patients are at high risk for CMV, and current antiviral drugs often …
Phase: PHASE2 • Sponsor: University Hospital, Lille • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC
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Stem cell infusions aim to tame COVID-19 inflammation
Disease control TerminatedThis study tested whether infusions of stem cells from donated fat tissue could help people with COVID-19. The trial planned to enroll 48 adults and compare four doses of stem cells against a placebo. The goal was to see if the treatment could reduce inflammation and improve oxyg…
Phase: PHASE2 • Sponsor: Hope Biosciences Research Foundation • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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Could a pill replace IV drips for septic shock? small trial halted early
Disease control TerminatedThis study tested whether the oral drug midodrine could help people with septic shock stop needing IV blood pressure support sooner. The trial planned to enroll many patients but was stopped early with only 10 participants. Because it was so small, we cannot draw firm conclusions…
Phase: PHASE3 • Sponsor: University of Virginia • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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Worm-Fighting combo pill tested in kids, but trial stopped early
Disease control TerminatedThis study tested a new pill combining two drugs (albendazole and ivermectin) to treat several types of intestinal worms in children and young adults aged 5 to 18. The goal was to see if the combination worked better than the standard single drug. However, the trial was terminate…
Phase: PHASE2, PHASE3 • Sponsor: Barcelona Institute for Global Health • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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Hydroxychloroquine trial for COVID-19 fizzles out
Disease control TerminatedThis early-phase study tested whether hydroxychloroquine, a drug used for malaria and autoimmune diseases, could reduce the amount of virus in adults with mild COVID-19 not needing oxygen. Only 8 people took part before the trial was stopped early. The study was too small to draw…
Phase: PHASE1 • Sponsor: Sanofi • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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Antibiotic teicoplanin tested for stubborn gut infection
Disease control TerminatedThis study tested the antibiotic teicoplanin (taken by mouth twice daily for 7 to 14 days) in 50 adults hospitalized with C. difficile infection causing diarrhea and colitis. The goal was to see if it could stop diarrhea and prevent it from coming back. The trial was terminated e…
Phase: PHASE4 • Sponsor: Sanofi • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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New hope against deadly molds? early trial cut short
Disease control TerminatedThis study tested a drug called fosmanogepix in 21 adults with invasive mold infections (like Aspergillus or rare molds) who had few other options. The trial was stopped early, so we have limited data on how well it works or its safety.
Phase: PHASE2 • Sponsor: Basilea Pharmaceutica • Aim: Disease control
Last updated Jun 26, 2026 17:54 UTC
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Kidney transplant patients get extra COVID shot in new trial
Disease control TerminatedThis phase 3 trial tested whether a dose of the Janssen COVID-19 vaccine could boost immunity in kidney transplant recipients who had already received two or three mRNA vaccine doses. The study enrolled 468 participants and also looked at reducing immunosuppression medication. Ho…
Phase: PHASE3 • Sponsor: Mark Stegall • Aim: Disease control
Last updated Jun 26, 2026 17:26 UTC
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Nasal spray aims to fight COVID-19, but trial halted early
Disease control TerminatedThis study tested a nasal spray called AD17002 in 180 adults with mild to moderate COVID-19. Participants received either a low dose, high dose, or placebo spray alongside standard care. The goal was to see if the spray speeds up recovery and improves symptoms. However, the trial…
Phase: PHASE2, PHASE3 • Sponsor: Advagene Biopharma Co. Ltd. • Aim: Disease control
Last updated Jun 26, 2026 16:12 UTC
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Stem cell shot for COVID-19 fizzles in small trial
Disease control TerminatedThis study tested whether a single infusion of stem cells from umbilical cord tissue (ProTrans®) could help hospitalized adults with severe COVID-19 avoid ventilators or death. The trial was stopped early after enrolling only 19 people, so we cannot draw firm conclusions. Both th…
Phase: PHASE2 • Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre • Aim: Disease control
Last updated Jun 26, 2026 15:19 UTC
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Hepatitis b cure hope fades as early trial ends
Disease control TerminatedThis small phase 2 trial tested whether giving hepatitis B antibodies (HBIG) could clear the hepatitis B surface antigen in people with chronic hepatitis B. Only 13 patients were enrolled before the study was terminated. The goal was to see if a 12-week course of injections could…
Phase: PHASE2 • Sponsor: Hannover Medical School • Aim: Disease control
Last updated Jun 26, 2026 13:38 UTC
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Fatty liver drug trial in HIV patients stalls after enrolling just 4 people
Disease control TerminatedThis study tested a drug called saroglitazar magnesium for nonalcoholic fatty liver disease (NAFLD) in people with HIV. The trial aimed to see if the drug could reduce liver fat over 24 weeks. However, the study was terminated early and only enrolled 4 participants, so no meaning…
Phase: PHASE2 • Sponsor: Zydus Therapeutics Inc. • Aim: Disease control
Last updated Jun 26, 2026 12:33 UTC
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Rapid COVID test studied for emergency triage
Diagnosis TerminatedThis study looked at using a fast, point-of-care COVID-19 test to help doctors quickly decide how to treat patients with serious heart or breathing problems. It involved 66 adults who already tested positive for COVID-19. The goal was to find the best way to collect samples (nose…
Sponsor: Ottawa Heart Institute Research Corporation • Aim: Diagnosis
Last updated Jun 27, 2026 12:33 UTC
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Fingerprint sweat may reveal COVID-19 infection
Diagnosis TerminatedThis study explored whether analyzing sweat from fingerprints using a special camera could quickly detect COVID-19. Researchers enrolled 66 adults who had tested positive or negative for COVID-19 within the past week. Participants provided a fingerprint sweat sample and a blood s…
Sponsor: National Cancer Institute (NCI) • Aim: Diagnosis
Last updated Jun 27, 2026 12:25 UTC
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Gene test aims to spot hidden infections after surgery
Diagnosis TerminatedThis study looked at whether changes in gene activity in blood cells can help doctors tell the difference between a normal inflammatory response after major surgery and a serious infection. Researchers planned to enroll 61 adults undergoing high-risk noncardiac surgery. The study…
Sponsor: St. Antonius Hospital • Aim: Diagnosis
Last updated Jun 27, 2026 12:24 UTC
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Can a One-Minute chair test predict COVID-19 hospital needs?
Diagnosis TerminatedThis study tested whether a one-minute sit-to-stand test could help emergency doctors decide if COVID-19 patients need hospital care. The test measures oxygen levels and breathing effort during repeated standing from a chair. The trial aimed to reduce unnecessary hospital stays b…
Phase: NA • Sponsor: University Hospital, Rouen • Aim: Diagnosis
Last updated Jun 27, 2026 08:13 UTC
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Infection-Fighting stitches tested for C-Sections, but trial stopped early
Prevention TerminatedThis study tested whether using stitches coated with an antibacterial agent (triclosan) could reduce infections after cesarean delivery. Over 1,100 women were planned to take part, but the trial was stopped early. Because it was terminated, we cannot draw firm conclusions about w…
Phase: PHASE4 • Sponsor: The University of Texas Medical Branch, Galveston • Aim: Prevention
Last updated Jun 27, 2026 14:01 UTC
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Monthly HIV prevention pill trial halted Mid-Study
Prevention TerminatedThis study tested a once-monthly pill called islatravir to prevent HIV infection in cisgender men and transgender women who have sex with men and are at high risk. About 494 participants were enrolled, but the trial was terminated early. The main goal was to check safety and see …
Phase: PHASE3 • Sponsor: Merck Sharp & Dohme LLC • Aim: Prevention
Last updated Jun 27, 2026 12:29 UTC
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New device aims to stop deadly infections in tiny preemies
Prevention TerminatedThis study tested a special multi-line device (Edelvaiss Multiline NEO) to see if it could prevent bloodstream infections in very premature infants (24-29 weeks) who need IV medications and nutrition. The device was compared to standard infusion sets. Unfortunately, the trial was…
Phase: NA • Sponsor: University Hospital, Lille • Aim: Prevention
Last updated Jun 27, 2026 12:23 UTC
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ERs could be key to boosting HPV shots in High-Risk adults
Prevention TerminatedThis study explored whether giving the HPV vaccine in the emergency department (ER) could help protect adults aged 18-45 who haven't been fully vaccinated. Researchers enrolled 34 participants and offered the vaccine during their ER visit, with follow-up doses at 2 and 6 months. …
Sponsor: University of Alabama at Birmingham • Aim: Prevention
Last updated Jun 27, 2026 12:09 UTC
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Phone app aims to boost HIV testing in young black men and transwomen
Prevention TerminatedThis study tested a mobile-friendly tool that helps young Black men and transwomen who have sex with men or transwomen pick the best HIV testing method for them, such as self-testing or clinic testing. The goal was to see if this personalized recommendation could increase how oft…
Phase: NA • Sponsor: New York Blood Center • Aim: Prevention
Last updated Jun 27, 2026 12:05 UTC
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Could a simple gas shield healthcare workers from COVID-19?
Prevention TerminatedThis study tested whether breathing in nitric oxide gas could prevent healthcare workers from catching COVID-19. The plan was to enroll 470 workers, but the trial was stopped early with only 24 participants. Workers in the treatment group inhaled the gas at the start and end of e…
Phase: PHASE2 • Sponsor: Massachusetts General Hospital • Aim: Prevention
Last updated Jun 27, 2026 11:04 UTC
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Wolbachia-Infected mosquitoes released to fight dengue, zika, and chikungunya
Prevention TerminatedThis trial tested a method to control mosquito-borne diseases like dengue, Zika, and chikungunya by releasing male Aedes aegypti mosquitoes infected with Wolbachia bacteria. These males mate with wild females, causing their eggs to die, which reduces the mosquito population. The …
Phase: NA • Sponsor: Michigan State University • Aim: Prevention
Last updated Jun 27, 2026 11:03 UTC
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New approach aims to boost HIV prevention in LGBTQ+ individuals struggling with addiction
Prevention TerminatedThis study tested a program to help HIV-negative transgender women and men who have sex with men who also have a substance use disorder stick with PrEP, a daily pill or shot that prevents HIV. Participants received counseling and text support, with extra help for those who strugg…
Phase: NA • Sponsor: Friends Research Institute, Inc. • Aim: Prevention
Last updated Jun 27, 2026 09:04 UTC
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Monthly HIV prevention pill tested in women – study halted early
Prevention TerminatedThis study tested a new monthly pill (islatravir) to see if it could prevent HIV infection better than a daily pill in 730 women at high risk. The trial was stopped early, so results are limited. The goal was to offer a more convenient prevention option.
Phase: PHASE3 • Sponsor: Merck Sharp & Dohme LLC • Aim: Prevention
Last updated Jun 27, 2026 09:01 UTC
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TB prevention study halted early – only 16 volunteers enrolled
Prevention TerminatedThis study aimed to see if a single dose of the BCG vaccine could prevent tuberculosis infection in healthy adults traveling to countries with high TB rates. Participants were randomly assigned to receive either BCG or a placebo. The study was terminated early and enrolled only 1…
Phase: PHASE3 • Sponsor: Henry M. Jackson Foundation for the Advancement of Military Medicine • Aim: Prevention
Last updated Jun 27, 2026 08:13 UTC
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Super-Sized flu shot for tots? study tests higher dose
Prevention TerminatedThis study tested whether a high-dose flu vaccine works better than the standard dose in preventing the flu in children aged 6 to 35 months. About 100 children took part, receiving either the high-dose or standard-dose shot. The study was stopped early, so results are limited.
Phase: PHASE3 • Sponsor: Sanofi Pasteur, a Sanofi Company • Aim: Prevention
Last updated Jun 27, 2026 08:06 UTC
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Antibody shield for the vulnerable: COVID-19 prevention trial in immunocompromised
Prevention TerminatedThis study tested whether a combination of antibodies (casirivimab+imdevimab) could prevent COVID-19 in people with weakened immune systems, such as transplant recipients or cancer patients. Participants received either the antibodies or a placebo as a shot under the skin. The tr…
Phase: PHASE3 • Sponsor: Regeneron Pharmaceuticals • Aim: Prevention
Last updated Jun 27, 2026 07:55 UTC
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Nasal spray could be new weapon against COVID-19
Prevention TerminatedThis study tested whether a nitric oxide nasal spray could prevent COVID-19 in people at risk of exposure. About 1,400 adults used the spray or a placebo for 28 days. The trial was terminated early, so final results are not available.
Phase: PHASE3 • Sponsor: Sanotize Research and Development corp. • Aim: Prevention
Last updated Jun 27, 2026 07:51 UTC
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Super-Sized flu shot tested for Seniors' heart and lung protection
Prevention TerminatedThis study compared a high-dose flu vaccine to the standard-dose shot in over 33,000 adults aged 65 and older. The goal was to see if the high-dose version could better prevent hospitalizations for heart and lung problems. The trial was terminated early, so the full picture is no…
Phase: PHASE3 • Sponsor: Sanofi Pasteur, a Sanofi Company • Aim: Prevention
Last updated Jun 26, 2026 17:31 UTC
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Mental health sessions may boost vaccine uptake in latinx communities
Prevention TerminatedThis study tested whether adding vaccine discussions to routine behavioral health visits could reduce hesitancy and increase COVID-19 and flu shots among Latinx adults with mental illness. Clinicians used motivational interviewing and could offer a warm handoff to a nurse for vac…
Phase: NA • Sponsor: Boston College • Aim: Prevention
Last updated Jun 26, 2026 17:00 UTC
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HIV drug fails to prove COVID-19 prevention in abandoned trial
Prevention TerminatedThis study tested whether a daily pill used for HIV (TAF/FTC) could prevent COVID-19 in healthcare workers at high risk of exposure. Over 1,300 workers were randomly assigned to get the drug or a placebo for 12 weeks. The trial was stopped early, so it's unclear if the drug had a…
Phase: PHASE3 • Sponsor: Hospital Italiano de Buenos Aires • Aim: Prevention
Last updated Jun 26, 2026 14:58 UTC
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Egg-Free flu vaccine tested in kids: could it be just as good?
Prevention TerminatedThis study compared a newer recombinant flu vaccine (RIV4, also called Supemtek or Flublok Quadrivalent) to the standard egg-based flu vaccine in 366 children aged 3 to 8 years. The goal was to see if the recombinant vaccine produced a similar immune response and was as safe. The…
Phase: PHASE3 • Sponsor: Sanofi Pasteur, a Sanofi Company • Aim: Prevention
Last updated Jun 26, 2026 14:42 UTC
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RSV drug trial for kids under 5 halted early – only 4 children enrolled
Symptom relief TerminatedThis study tested an oral antiviral drug called obeldesivir in children from birth to under 5 years old who had RSV infection. The goal was to see if the drug is safe and helps reduce symptoms faster. However, the trial was stopped early and only enrolled 4 participants, so the r…
Phase: PHASE2 • Sponsor: Gilead Sciences • Aim: Symptom relief
Last updated Jun 27, 2026 13:04 UTC
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Youth HIV study tests talking circles for better mental health
Symptom relief TerminatedThis study tested whether a group therapy program, led by trained youth leaders, could improve mental health and help young people with HIV stick to their medication. About 484 youth in low-resource settings took part. The program used trauma-informed counseling adapted to local …
Phase: NA • Sponsor: International Maternal Pediatric Adolescent AIDS Clinical Trials Group • Aim: Symptom relief
Last updated Jun 27, 2026 12:37 UTC
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Vitamin c trial for elderly pneumonia fizzles out
Symptom relief TerminatedThis study looked at whether giving vitamin C to elderly patients hospitalized with pneumonia could improve their breathing and daily function. Only 9 people took part before the study was stopped early. Because it was so small, we can't say if vitamin C helps or not.
Phase: PHASE2 • Sponsor: University Hospital, Bordeaux • Aim: Symptom relief
Last updated Jun 27, 2026 12:36 UTC
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Mindfulness app for anxiety in underserved groups fizzles out early
Symptom relief TerminatedThis study tested a smartphone app that teaches mindfulness meditation to help Black and Latino adults with anxiety during the COVID-19 pandemic. About 400 participants were assigned to one of two mindfulness programs or a waitlist. The trial was terminated early, so we don't hav…
Phase: NA • Sponsor: University of North Carolina, Chapel Hill • Aim: Symptom relief
Last updated Jun 27, 2026 12:33 UTC
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HIV-Positive Men's mental health study shuts down after just one participant
Symptom relief TerminatedThis study aimed to see if acceptance and commitment therapy (ACT), a type of talk therapy, could help HIV-positive men with mental health issues like stress and anxiety. Only one person enrolled before the study was stopped early. Because of this, no meaningful results were obta…
Phase: NA • Sponsor: University of Alabama at Birmingham • Aim: Symptom relief
Last updated Jun 27, 2026 12:09 UTC
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Pharmacists step in to treat bladder infections in women
Symptom relief TerminatedThis study looked at whether a special protocol used by community pharmacists in France can help women with simple bladder infections (cystitis) get relief more quickly. The goal was to reduce symptoms and avoid unnecessary trips to the doctor or emergency room. The study include…
Phase: NA • Sponsor: University Hospital, Angers • Aim: Symptom relief
Last updated Jun 27, 2026 11:01 UTC
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Salt water gargle study for COVID-19 fizzles out early
Symptom relief TerminatedThis study tested whether rinsing the nose and gargling with salt water could help people with suspected or confirmed COVID-19 feel better faster. Only 16 adults in the UK took part before the study was stopped early. The goal was to see if this simple home remedy could reduce ho…
Phase: NA • Sponsor: University of Edinburgh • Aim: Symptom relief
Last updated Jun 27, 2026 09:09 UTC
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New sedation approach may help septic shock patients breathe on their own sooner
Symptom relief TerminatedThis study tested whether a gas sedative (isoflurane) could help patients with septic shock wake up and get off a breathing machine faster than standard IV sedation (midazolam). The goal was to reduce complications from long-term sedation and ventilation. Only one patient was enr…
Phase: PHASE4 • Sponsor: University Hospital, Rouen • Aim: Symptom relief
Last updated Jun 27, 2026 09:03 UTC
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CBD shows promise for emotional health in HIV patients
Symptom relief TerminatedThis study tested whether synthetic cannabidiol (CBD) could help people living with HIV who have a condition called alexithymia, which makes it hard to recognize and describe emotions. Participants took either CBD or a placebo for 4 weeks. The goal was to see if CBD could improve…
Phase: PHASE2 • Sponsor: University of California, San Diego • Aim: Symptom relief
Last updated Jun 27, 2026 08:14 UTC
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New pill aims to quiet debilitating cough in lung scarring disease
Symptom relief TerminatedThis study tested an experimental drug called BI 1839100 in adults with idiopathic pulmonary fibrosis (IPF) or progressive pulmonary fibrosis (PPF) who have a chronic cough. Participants took different doses of the drug or a placebo for 12 weeks. The goal was to see if the drug c…
Phase: PHASE2 • Sponsor: Boehringer Ingelheim • Aim: Symptom relief
Last updated Jun 27, 2026 08:12 UTC
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Exercise and diet boost mental health in heart infection patients
Symptom relief TerminatedThis study tested whether adding physical rehabilitation and personalized nutrition to standard care helps patients with infective endocarditis (a serious heart infection) feel better during their hospital stay. The goal was to improve mental health and quality of life. The study…
Phase: NA • Sponsor: Johannes Grand • Aim: Symptom relief
Last updated Jun 27, 2026 08:04 UTC
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Ancient herbal remedy put to the test against COVID-19
Symptom relief TerminatedThis small pilot study tested whether a traditional Chinese medicine called Xuanfei Baidu granules is safe and acceptable for people with mild to moderate COVID-19. Only 10 adults were enrolled before the study was stopped early. The main goal was to see how many people would agr…
Phase: PHASE2 • Sponsor: Darcy Spicer • Aim: Symptom relief
Last updated Jun 27, 2026 08:04 UTC
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Lyme arthritis pain study halted early – what we know
Symptom relief TerminatedThis study aimed to see if taking NSAIDs (like naproxen) on a regular schedule could reduce arthritis symptoms and prevent long-term joint problems in people with Lyme disease. Only 3 participants were enrolled before the study was stopped, so no clear conclusions can be drawn. T…
Phase: PHASE3 • Sponsor: Desiree Neville, MD • Aim: Symptom relief
Last updated Jun 27, 2026 07:58 UTC
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Calm app tested on stressed doctors – but study cut short
Symptom relief TerminatedThis study looked at whether using the Calm meditation app could help medical residents and fellows at Banner University Medical Center Phoenix feel less stressed, anxious, or burned out during the COVID-19 pandemic. Only 7 people signed up, and the study was stopped early, so we…
Phase: NA • Sponsor: University of Arizona • Aim: Symptom relief
Last updated Jun 27, 2026 07:56 UTC
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Long COVID rehab study halted early – what we know
Symptom relief TerminatedThis study looked at whether a supervised exercise and pulmonary rehabilitation program could help people with Long COVID feel better and move more easily. Researchers measured changes in aerobic capacity, fatigue, and quality of life in 21 adults who had COVID at least 12 weeks …
Phase: NA • Sponsor: Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC
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HIV patients may age faster: study probes skin, muscle, and bone health
Knowledge-focused TerminatedThis study compared signs of aging in 123 HIV-infected adults to the general population. Researchers measured bone density, muscle strength, skin changes, and thinking abilities. The goal was to understand if HIV speeds up aging in these areas. No new treatment was tested; it was…
Phase: NA • Sponsor: University Hospital, Bordeaux • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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COVID-19 vaccine safety checked in cancer immunotherapy patients
Knowledge-focused TerminatedThis study aimed to see if COVID-19 vaccines cause more side effects in cancer patients receiving immunotherapy. Researchers planned to track 125 patients from several hospitals in France, recording any local or systemic side effects. The study was terminated early, so the full r…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:01 UTC
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Could a common virus trigger thyroid troubles?
Knowledge-focused TerminatedThis study investigated whether polyomaviruses (a type of common virus) are found more often in people with autoimmune thyroiditis or goiters. Researchers compared virus presence in blood, urine, and thyroid tissue from 49 patients undergoing thyroid surgery. The goal was to see …
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:07 UTC
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Scientists collect samples from COVID-19 patients to unlock virus secrets
Knowledge-focused TerminatedThis study collected blood, urine, stool, and respiratory samples from 615 COVID-19 patients and caregivers at Bordeaux University Hospital. The goal was to build a biobank for research on the virus and disease. The study was terminated early, but the samples may still help scien…
Sponsor: University Hospital, Bordeaux • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:07 UTC
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COVID-19 may harm the brain in ways scans Can't see
Knowledge-focused TerminatedThis study looked for hidden brain damage in 38 hospitalized COVID-19 patients. Instead of using standard MRI scans, researchers used electrical tests to check how well the brainstem was working. The goal was to find subtle nervous system problems that might not show up on regula…
Phase: NA • Sponsor: University Hospital, Bordeaux • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC
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Anesthesia drug study halted after just 3 patients
Knowledge-focused TerminatedThis study aimed to see if skipping a type of muscle relaxant during general anesthesia could lower the risk of serious lung complications in high-risk surgery patients. The trial was terminated early after enrolling only 3 participants, so no meaningful conclusions can be drawn.…
Phase: PHASE4 • Sponsor: Beth Israel Deaconess Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:03 UTC
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Web tool aims to ease tough COVID conversations
Knowledge-focused TerminatedThis study tested a web-based guide to help people have conversations about COVID-19. It enrolled 30 adults who spoke English or Spanish. The guide offered virtual conversations tailored to different concerns. The study was terminated early, so results are limited.
Sponsor: Wake Forest University Health Sciences • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:02 UTC
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ER study aims to perfect antibiotic dosing for urinary infections
Knowledge-focused TerminatedThis study aimed to find the best dose of the antibiotic ceftriaxone for adults with urinary tract infections in the emergency department. Researchers measured how the drug behaves in the body to ensure it stays at effective levels long enough to kill bacteria. The study was stop…
Sponsor: University Hospital, Rouen • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:37 UTC
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COPD study investigates why patients struggle to fight lung infections
Knowledge-focused TerminatedThis study looked at whether a weak immune response to bacteria in COPD patients leads to more lung infections and flare-ups. Researchers collected sputum, blood, and nasal swabs from 23 hospitalized COPD patients during a flare-up and again 8 to 16 weeks later. The goal was to m…
Phase: NA • Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:36 UTC
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New X-Ray tech could cut radiation and save time for hip surgery patients
Knowledge-focused TerminatedThis study looked at whether a newer, low-dose X-ray system (EOSedge) produces images good enough for planning hip replacement or revision surgery, compared to standard digital X-rays. About 97 adults who needed hip surgery X-rays took part. The goal was to see if using just one …
Phase: NA • Sponsor: University Hospital, Montpellier • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:32 UTC
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Donor milk experiment halted: did matching help tiny babies?
Knowledge-focused TerminatedThis study looked at whether matching donor breast milk to a mother's secretor type could improve gut bacteria in very preterm infants. Researchers planned to compare matched versus standard donor milk in babies born before 34 weeks. The study was stopped early and included only …
Phase: NA • Sponsor: University of Manitoba • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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Lung cancer study aims to predict dangerous lung inflammation
Knowledge-focused TerminatedThis study followed 83 people with advanced non-small cell lung cancer who were starting standard treatments. The goal was to collect information to help develop a digital tool that can spot early signs of pneumonitis/ILD, a serious lung inflammation that can occur as a side effe…
Sponsor: AstraZeneca • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Scientists investigate mpox in severely weakened immune systems
Knowledge-focused TerminatedThis study looked at how the mpox virus spreads and how the immune system responds in people with advanced HIV. Researchers tracked the virus in different body samples and measured immune markers to better understand severe illness. The goal is to use these findings to improve tr…
Sponsor: Centers for Disease Control and Prevention • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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New ICU cockpit software aims to predict brain complications before they happen
Knowledge-focused TerminatedThis study tested a software platform called ICU Cockpit that collects and displays vital signs and other data from brain-injury patients in the intensive care unit. The goal was to help doctors make faster, better decisions and to predict complications like strokes or unstable c…
Phase: NA • Sponsor: Emanuela Keller • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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Leishmaniasis drug candidate tested in humans for first time – study halted early
Knowledge-focused TerminatedThis was a first-in-human study to check the safety and how the body processes a single dose of GSK3494245, a potential treatment for leishmaniasis. It involved 59 healthy adults who received up to three increasing doses of the drug or a placebo. The study was terminated early, s…
Phase: PHASE1 • Sponsor: GlaxoSmithKline • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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AI analyzes 100,000 COVID-19 cases to predict who gets worst outcomes
Knowledge-focused TerminatedThis study used artificial intelligence to analyze electronic health records from 100,000 COVID-19 patients across multiple hospitals. The goal was to identify factors that predict whether a patient would be hospitalized, need ICU care, or die. The study was terminated early, so …
Sponsor: Savana Research • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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Web tool aims to boost HIV testing among black women in the south
Knowledge-focused TerminatedThis study tested a web-based program to help Black women in Texas use HIV and STI home tests and connect to treatment or PrEP. The program included five sessions with goal-setting and action plans. Only 31 women enrolled before the study was stopped early, so the findings are li…
Phase: NA • Sponsor: Johns Hopkins Bloomberg School of Public Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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Rouen hospital checks accuracy of COVID-19 antibody tests
Knowledge-focused TerminatedThis study aimed to check how accurate several COVID-19 antibody tests are. Researchers used blood samples from 101 adults, including some taken before the pandemic and some from people with other infections. The goal was to see which tests best detect past COVID-19 infection.
Phase: NA • Sponsor: University Hospital, Rouen • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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Scientists hunt for clues to tell infection apart from inflammation in Kids' joints
Knowledge-focused TerminatedThis study looked for new markers in blood and joint fluid to help doctors tell the difference between septic arthritis (a joint infection) and juvenile idiopathic arthritis (an inflammatory condition) in children. Researchers planned to analyze samples from 100 children under 15…
Sponsor: University Hospital, Montpellier • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Vaccine study aims to unlock secrets of immune memory
Knowledge-focused TerminatedThis study looked at how the hepatitis B vaccine triggers immune cells called B cells to form germinal centers, where antibodies become stronger. Researchers wanted to understand if memory B cells return to these centers after a booster shot. The goal was to learn how to design b…
Phase: PHASE4 • Sponsor: Rockefeller University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC
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Scientists hunt for genetic and environmental clues in rare lung disease
Knowledge-focused TerminatedThis study aimed to describe the features and natural history of idiopathic interstitial pneumopathy, a group of rare lung diseases, in both children and adults. Researchers planned to collect data from 1,600 participants, including medical history, imaging, and genetic tests, to…
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC
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New lung camera could replace needle biopsies
Knowledge-focused TerminatedThis study aimed to see if a tiny camera on a thin tube (bronchoscopy) could help doctors diagnose diffuse lung diseases without needing a surgical lung biopsy. The camera takes live microscopic images of the air sacs. The study was stopped early, but it involved 38 adults with c…
Phase: NA • Sponsor: University Hospital, Rouen • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC
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Blood pressure experiment in sepsis halted early – kidney protection still unclear
Knowledge-focused TerminatedThis study tested whether raising the blood pressure target from 65 mmHg to 85 mmHg in patients with septic shock could help prevent kidney injury. Researchers used a drug called norepinephrine to adjust blood pressure and monitored kidney function. The trial was stopped early an…
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC
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Smart vest monitors COVID patients
Knowledge-focused TerminatedThis study tested a special vest that tracks health data like heart rate and breathing in people hospitalized with COVID-19. The goal was to see if the vest could help doctors spot worsening symptoms early. Only 15 adults took part before the study ended early.
Sponsor: Nanowear Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Arthritis drugs and COVID: study probes immune response
Knowledge-focused TerminatedThis study looked at how immunosuppressive medications used for rheumatoid arthritis and spondyloarthritis affect the body's ability to fight COVID-19. Researchers measured viral load and immune responses in 150 patients and their infected family members. The goal was to understa…
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:02 UTC
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Gene hunt: why some people get worse blood infections
Knowledge-focused TerminatedThis study looked at whether certain genetic differences in the immune system make some people more likely to develop severe bloodstream infections from E. coli or Staphylococcus aureus bacteria. Researchers planned to analyze blood samples from 60 patients to find mutations link…
Sponsor: Centre Hospitalier Universitaire de Nice • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Study aims to find best first treatment for painful breast abscesses
Knowledge-focused TerminatedThis study looked at 500 patients with breast abscesses to see which first treatment works best: draining with a needle (aspiration) or making a small cut (incision and drainage). The goal was to find risk factors that lead to needing more than one treatment. The study was stoppe…
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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New brain scanner peers into COVID's neurological mysteries
Knowledge-focused TerminatedThis pilot study tested a new brain PET-MR scanner to see if it can capture clear images of brain metabolism and blood flow in people who had COVID-19 and those who did not. Only 3 participants were enrolled before the study ended early. The goal was to develop an imaging protoco…
Phase: NA • Sponsor: Stanford University • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC
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Scientists hunt for early warning signs of kidney failure
Knowledge-focused TerminatedThis study aimed to find substances in blood and urine that could signal kidney damage earlier than current tests. Researchers compared samples from healthy volunteers, people with low fluid levels, those at high risk for kidney failure, and patients with acute kidney failure. Th…
Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Sleep apnea machine tested for IPF lung health – but study stopped early
Knowledge-focused TerminatedThis study looked at whether using a CPAP machine at night could reduce abnormal acid reflux and lung inflammation in people with idiopathic pulmonary fibrosis (IPF) who also have sleep apnea. Only 7 people enrolled before the study was terminated early. The goal was to measure c…
Phase: NA • Sponsor: University of Arizona • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Scientists hunt for hidden family genes behind painful skin disease
Knowledge-focused TerminatedThis study aimed to find a genetic link or family trait that connects people with Hidradenitis Suppurativa (HS), a painful skin condition. Researchers collected blood or saliva samples from 97 participants, including affected individuals and their family members, to analyze DNA f…
Sponsor: University of Chicago • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC
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Vaccine antibody check: how long does protection last?
Knowledge-focused TerminatedThis study followed women who previously received 1 to 3 doses of an experimental Group B Strep (GBS) vaccine. The goal was to see how long their immune antibodies lasted by taking yearly blood samples for 2 to 5 years. No new vaccine or treatment was given—only observation.
Sponsor: Minervax ApS • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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Blood pressure drug study in septic shock halted early
Knowledge-focused TerminatedThis observational study aimed to understand why some septic shock patients respond better to the drug vasopressin. Researchers planned to compare blood markers, heart ultrasound images, and tissue oxygen levels between responders and non-responders. However, the study was termin…
Sponsor: The Cleveland Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC
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Nose drops with friendly bacteria could pave way for meningitis vaccine
Knowledge-focused TerminatedThis study gave healthy adults nose drops containing a harmless bacteria (N. lactamica) to see how the body's immune system responds. The goal is to learn if the immune response is the same whether the bacteria is cleared after 4 days or 14 days. This information will help design…
Phase: NA • Sponsor: University Hospital Southampton NHS Foundation Trust • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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Scientists investigate why ventilators may worsen lung infections
Knowledge-focused TerminatedThis study looked at how mechanical ventilation (breathing machines) affects the energy centers (mitochondria) of immune cells in patients with severe lung infections and acute respiratory distress syndrome (ARDS). Researchers aimed to understand why some patients get worse despi…
Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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Flu vaccine study halted after just 2 volunteers
Knowledge-focused TerminatedThis study aimed to compare how the immune system responds to two different seasonal flu vaccines given at the same time. Healthy adults aged 18-49 who had not received a flu shot in at least three years were eligible. The study was terminated early and only enrolled 2 participan…
Phase: EARLY_PHASE1 • Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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Can cheap text messages boost HIV retesting? pilot study seeks answers
Knowledge-focused TerminatedThis pilot study tested several low-cost behavioral nudges, like videos and text messages, to encourage HIV retesting among 98 adults at higher risk of HIV in rural Kenya and Uganda. The goal was to see which approaches were acceptable and feasible, so the best ones could be used…
Phase: NA • Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:14 UTC
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Sticker shock: simple reminder may cut unnecessary IV antibiotic use
Knowledge-focused TerminatedThis study tested whether placing a reminder sticker on the charts of adult hospital patients receiving IV fluoroquinolone antibiotics would encourage doctors to switch them to oral pills sooner. The trial involved 168 patients at a single hospital in Thailand. Unfortunately, the…
Phase: NA • Sponsor: Mahidol University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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Rural pharmacists get virtual coaching to tackle vaccine hesitancy
Knowledge-focused TerminatedThis study looked at whether virtual coaching helps rural pharmacists better counsel patients who are hesitant about COVID-19 vaccines. Sixteen pharmacies took part, first receiving standard training and then adding one-on-one video coaching. The main goal was to see if coaching …
Phase: NA • Sponsor: University of North Carolina, Chapel Hill • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC
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MRI scans aim to uncover hidden ear damage in CMV survivors
Knowledge-focused TerminatedThis study looked at whether people born with cytomegalovirus (CMV) infection who have hearing loss or balance problems also have a condition called endolymphatic hydrops (fluid buildup in the inner ear). Researchers used a special MRI scan with a contrast dye to check for this f…
Sponsor: Fondation Ophtalmologique Adolphe de Rothschild • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC
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Hepatitis c blood study halted early: what it means
Knowledge-focused TerminatedThis study aimed to see how often people with chronic hepatitis C have a blood condition called monoclonal B-cell lymphocytosis (MBL), and whether treating hepatitis C affects MBL. Researchers planned to enroll 29 participants and compare blood samples before and after hepatitis …
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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Cancer Patients' COVID risk explored in terminated study
Knowledge-focused TerminatedThis study aimed to understand how COVID-19 affects people with cancer, especially those receiving treatment. Researchers planned to measure how many cancer patients had COVID-19 without symptoms and how their immune systems responded. The study was terminated early, so results a…
Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Scientists probe immune cells in pneumonia to unlock ARDS secrets
Knowledge-focused TerminatedThis study looked at how certain immune cells, called non-conventional T cells, behave in patients with severe pneumonia and acute respiratory distress syndrome (ARDS). Researchers collected blood and airway samples from 258 intensive care unit patients to track these cells over …
Sponsor: University Hospital, Tours • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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COVID-19's hidden heart damage: study aims to find clues
Knowledge-focused TerminatedThis study followed 80 adults who recovered from COVID-19 to check for heart problems. Participants had heart exams and blood tests one month and one year after recovery. The goal was to understand how often and what kind of heart issues occur after COVID-19, so doctors can bette…
Sponsor: Assistance Publique Hopitaux De Marseille • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Rabies treatment safety study in kids halted early
Knowledge-focused TerminatedThis study aimed to check the safety of a rabies immune globulin shot (HyperRAB) in children who were treated after an animal bite. It included 35 kids aged 17 and under across several emergency rooms. The study was stopped early, so results are limited, but the goal was to see i…
Sponsor: The Methodist Hospital Research Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Updated pfizer Shot's Real-World power under review
Knowledge-focused TerminatedThis study aimed to measure how well the 2024-2025 Pfizer COVID-19 vaccine prevents symptomatic infection in people visiting CVS MinuteClinics. Researchers planned to compare vaccinated and unvaccinated patients across age groups and variant periods. However, the study was termin…
Sponsor: Pfizer • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC
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Smart band tracks COVID-19 breathing trouble
Knowledge-focused TerminatedThis study tested a special band called AirGo to monitor breathing patterns in hospitalized COVID-19 patients with respiratory failure. The goal was to see if the band could detect early signs of worsening breathing, helping doctors decide when to use a breathing tube. The study …
Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:55 UTC
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Scientists track HPV's secret life in young women
Knowledge-focused TerminatedThis study followed 190 young women to learn how the body handles new HPV infections. Researchers measured virus levels, immune cells, and other factors over time. The goal was to understand why some infections clear quickly while others persist. No treatment was given; this was …
Phase: NA • Sponsor: University Hospital, Montpellier • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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HIV study tracks daily movement in NYC
Knowledge-focused TerminatedThis study looked at how much physical activity and sitting time people with HIV in New York City get. Participants wore a small device called an accelerometer for a week to track their movement. The goal was to understand how activity levels relate to overall health. The study w…
Sponsor: Queens College, The City University of New York • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC
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HIV drugs may weaken bones: new study investigates
Knowledge-focused TerminatedThis study looked at bone density in HIV-positive men to see if antiretroviral drugs cause bone thinning. Researchers compared men starting HIV treatment with those not yet on therapy over two years. The goal was to understand why bone loss is more common in HIV patients.
Phase: NA • Sponsor: University Hospital, Strasbourg, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Early safety test of iCP-NI drug halted before completion
Knowledge-focused TerminatedThis early-phase study tested the safety and tolerability of an experimental drug called iCP-NI in 24 healthy adults. Participants received either the drug or a placebo by intravenous infusion. The trial was terminated, so no conclusions about effectiveness can be drawn.
Phase: PHASE1 • Sponsor: Cellivery Therapeutics, Inc. • Aim: Knowledge-focused
Last updated Jun 26, 2026 19:00 UTC
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Hepatitis b patients under the microscope: new study observes Real-World treatments
Knowledge-focused TerminatedThis study observed over 1,700 adults with chronic hepatitis B in the US and Canada to understand how the disease progresses and how treatments are used in everyday medical practice. Researchers collected data from both academic and community clinics to build a real-world picture…
Sponsor: Target PharmaSolutions, Inc. • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:05 UTC
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COVID-19 vaccine response under scrutiny in autoimmune patients
Knowledge-focused TerminatedThis study looked at how well the COVID-19 vaccine triggers an immune response in people with autoimmune or inflammatory diseases who take immunosuppressants or biologics. Researchers took blood samples before vaccination and at several points after to measure antibodies and T-ce…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:24 UTC
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Real-World antibiotic study cut short: what we can learn
Knowledge-focused TerminatedThis study tracked how the antibiotic ceftazidime-avibactam is used in real hospital settings in China for serious infections like pneumonia and abdominal infections. Researchers planned to enroll 450 patients but the study was terminated early. The goal was to see how often the …
Sponsor: Pfizer • Aim: Knowledge-focused
Last updated Jun 26, 2026 13:39 UTC
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COVID-19's hidden toll on the retina: eye scans reveal damage
Knowledge-focused TerminatedThis study aimed to collect eye scans from people who had COVID-19 to see if the virus caused damage to the retina, the light-sensitive tissue at the back of the eye. Researchers planned to compare severe and mild COVID-19 cases, but the study was stopped early and only enrolled …
Sponsor: Centre Hospitalier Intercommunal Creteil • Aim: Knowledge-focused
Last updated Jun 26, 2026 12:34 UTC