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Could aspirin or ibuprofen help beat TB faster?

NCT ID NCT04575519

Terminated Disease control Sponsor: Fundació Institut Germans Trias i Pujol Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether adding aspirin or ibuprofen to standard tuberculosis (TB) treatment helps patients recover more quickly. It included 426 adults with drug-sensitive or drug-resistant TB. The trial was terminated early, so the results are not conclusive.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
acetylsalicylic acid (aspirin) and ibuprofen
What this could lead to
If successful, adding common pain relievers could speed up recovery from tuberculosis and reduce treatment time.
What could go wrong
The trial was terminated early, so we don't have clear evidence it works. Aspirin and ibuprofen also carry risks like bleeding or stomach issues.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

infectious disease latent tuberculosis infection multidrug-resistant tuberculosis pulmonary tuberculosis tuberculosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

TUBERCULOSIS INFECTION TUBERCULOSIS, MDR TUBERCULOSIS, PULMONARY

Contacts and locations

Locations

  • National Center for Tuberculosis and Lung Diseases

    Tbilisi, Georgia

  • PHRU- Matlosana, Tshepong Hospital MDR Unit

    Klerksdorp, Matlosana, South Africa

  • Perinatal HIV Unit (PHRU)- Chris Hani Baragwanath Hospital

    Soweto, Johannesburg, 1864, South Africa

More trials for these conditions

Other studies related to the condition(s) this trial covers.