Quick test could spare kids from strong antibiotics for UTIs

NCT ID NCT05066854

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested whether a rapid lab test (looking for integrons in urine) could help doctors choose a narrow-spectrum antibiotic instead of a broad-spectrum one for children with fever and a urinary tract infection. The goal was to see if this approach works as well as standard care while using fewer strong antibiotics. The trial was stopped early and included only 36 children, so the findings are limited.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
integron PCR test to guide antibiotic choice
What this could lead to
If successful, this approach could reduce the use of broad-spectrum antibiotics in children with urinary tract infections, helping to slow antibiotic resistance.
What could go wrong
The trial was terminated early with only 36 participants, so results are limited. The test may not be accurate enough in all settings, and narrow-spectrum antibiotics might still fail if the bacteria are resistant.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Bordeaux university Hospital

    Bordeaux, 33000, France

  • Limoges university Hospital

    Limoges, 87042, France

  • Montpellier university Hospital

    Montpellier, 34000, France

  • Toulouse university Hospital

    Toulouse, 31000, France

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