Quick test could spare kids from strong antibiotics for UTIs
NCT ID NCT05066854
First seen Jun 27, 2026 ยท Last updated Jun 27, 2026
Summary
This study tested whether a rapid lab test (looking for integrons in urine) could help doctors choose a narrow-spectrum antibiotic instead of a broad-spectrum one for children with fever and a urinary tract infection. The goal was to see if this approach works as well as standard care while using fewer strong antibiotics. The trial was stopped early and included only 36 children, so the findings are limited.
What this could mean
Our plain-language read of the trial. This is informational only โ not medical advice or a prediction.
- Active substance
- integron PCR test to guide antibiotic choice
- What this could lead to
- If successful, this approach could reduce the use of broad-spectrum antibiotics in children with urinary tract infections, helping to slow antibiotic resistance.
- What could go wrong
- The trial was terminated early with only 36 participants, so results are limited. The test may not be accurate enough in all settings, and narrow-spectrum antibiotics might still fail if the bacteria are resistant.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Bordeaux university Hospital
Bordeaux, 33000, France
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Limoges university Hospital
Limoges, 87042, France
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Montpellier university Hospital
Montpellier, 34000, France
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Toulouse university Hospital
Toulouse, 31000, France
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