COVID antibody drug tested in kids – but study stopped early

NCT ID NCT05092581

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a single dose of casirivimab+imdevimab (REGN-COV2) in children hospitalized with COVID-19. The goal was to see how the drug behaves in the body and whether it is safe. However, the study was terminated early and only enrolled 2 participants, so we have very little information from it.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
casirivimab+imdevimab (REGN-COV2, a combination of two monoclonal antibodies)
What this could lead to
If successful, this could provide a treatment option for hospitalized children with COVID-19.
What could go wrong
This was a very early (Phase 1) study that was terminated after enrolling only 2 participants, so results are extremely limited and may not be reliable.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Le Bonheur Children's Hospital

    Memphis, Tennessee, 38103, United States

  • State University of New York at Stony Brook

    Stony Brook, New York, 11794, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.