Experimental immune cell therapy for transplant viruses shows early promise but study halted
NCT ID NCT04364178
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-stage trial tested whether specially grown immune cells could help transplant patients fight off stubborn viral infections. The study included 8 people who had received a stem cell or organ transplant and had ongoing infections with adenovirus, CMV, or EBV. The approach aimed to boost the body's defenses without the long wait and high cost of personalized treatments. The study was terminated early, so results are limited.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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UPMC (University of Pittsburgh Medical Center)
Pittsburgh, Pennsylvania, 15224, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can specially grown immune cells from donors beat viruses that won't go away?
- Immune cell levels may predict who will develop severe CMV after transplant
- Lab-Grown immune cells take aim at Life-Threatening viruses in vulnerable patients
- Hidden immune fire: could CMV or autoimmunity be fueling HIV-Related inflammation?
- Newborn blood spots may reveal hidden risks from common virus