Lab-Grown immune cells take aim at Life-Threatening viruses in vulnerable patients
NCT ID NCT06027879
First seen Jun 29, 2026 · Last updated Jun 30, 2026 · Updated 1 time
Summary
This study tests whether specially grown immune cells can fight three common viruses—adenovirus, CMV, and EBV—in people whose immune systems are weak due to a stem cell or organ transplant, or an inherited immune disorder. The cells are made from a donor's blood and trained to recognize and attack the virus. The goal is to see if this treatment is safe and can clear the infection when standard therapies have failed.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
virus-specific T cells made using gamma capture technology
What this could lead to
If it works, this approach could offer a faster, more affordable way to treat dangerous viral infections in people with compromised immune systems, potentially saving lives.
What could go wrong
This is an early-phase trial with only 25 participants, so results may not apply to everyone. There is a risk of graft-versus-host disease or other immune reactions.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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UPMC Children's Hospital of Pittsburgh
Pittsburgh, Pennsylvania, 15224, United States