Hiprex trial for recurrent UTIs halted early – little data to go on
NCT ID NCT04709601
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study aimed to see if Hiprex (methenamine hippurate) could reduce recurrent urinary tract infections in women aged 50 to 85. Participants took Hiprex daily for a year, and researchers counted infections and antibiotic use. However, the trial was terminated early with only 14 participants, so we have very limited information on whether it works.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
methenamine hippurate (Hiprex)
What this could lead to
If it worked, this could offer a non-antibiotic option to reduce recurrent urinary tract infections in older women.
What could go wrong
The trial was terminated early and enrolled only 14 participants, so results are very limited. It is unclear if Hiprex effectively prevents UTIs or reduces antibiotic use.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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UT-Southwestern Medical Center
Dallas, Texas, 75390, United States