Experimental drug auxora tested in critical COVID-19 lung patients
NCT ID NCT04661540
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This small Phase 2 trial tested an experimental drug called Auxora in 10 patients with critical COVID-19 pneumonia who were on ventilators. The goal was to see how the drug affected immune cells in the lungs and to check its safety. The study was terminated early, so results are limited.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Auxora (CM4620-IE)
What this could lead to
If successful, Auxora could help control severe immune reactions in critical COVID-19 pneumonia, potentially improving outcomes for ventilated patients.
What could go wrong
This was a very small, early-phase trial (only 10 participants) that was terminated early, so results are limited. The drug may not show clear benefit or could have side effects.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Northwestern Memorial Hospital
Chicago, Illinois, 60611, United States