COVID-19 drug trial halted early: only 16 patients enrolled
NCT ID NCT04880109
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tested an experimental drug called APX-115 in hospitalized patients with mild to moderate COVID-19. The goal was to see if it was safe and could help people recover faster. However, the trial was stopped early and only 16 people took part, so we don't have enough information to know if the drug works or is safe.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
APX-115 (oral capsule)
What this could lead to
If it worked, APX-115 could offer a new oral treatment option for mild to moderate COVID-19, potentially speeding recovery.
What could go wrong
The trial was terminated early with only 16 participants, far short of the planned 80. This means results are very limited and no conclusions can be drawn about effectiveness or safety.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Anne Arundel Medical Center
Annapolis, Maryland, 21401, United States
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FASN, FAHA; John L. McClellan Memorial Veterans Hospital
Little Rock, Arkansas, 72205, United States
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FCCP; Jamaica Hospital Medical Center
Jamaica, New York, 11418, United States
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MSc, FAAN; Metro Health Hospital - Professional Building
Wyoming, Michigan, 49519, United States
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Medical City Fort Worth
Fort Worth, Texas, 76104, United States
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TriHealth Bethesda North Hospital
Cincinnati, Ohio, 45242, United States