COVID-19 vaccine response under scrutiny in autoimmune patients

NCT ID NCT04870411

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study looked at how well the COVID-19 vaccine triggers an immune response in people with autoimmune or inflammatory diseases who take immunosuppressants or biologics. Researchers took blood samples before vaccination and at several points after to measure antibodies and T-cells. The study was terminated early, so results are limited.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

COVID-19 vaccine (immune response measured via blood samples)

What this could lead to

If successful, this could help doctors understand how well COVID-19 vaccines work in people with autoimmune diseases taking immune-suppressing drugs.

What could go wrong

The study was terminated early with only 78 participants, so results may be limited and not apply to all patients. Immune response may still be weak in some groups.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

autoimmune disease COVID-19 inflammatory disease systemic lupus erythematosus systemic sclerosis uveitis vasculitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Internal medicine Service - Cochin Hospital

    Paris, 75014, France