COPD study investigates why patients struggle to fight lung infections

NCT ID NCT02655302

Terminated Knowledge-focused Sponsor: University Hospital, Lille Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether a weak immune response to bacteria in COPD patients leads to more lung infections and flare-ups. Researchers collected sputum, blood, and nasal swabs from 23 hospitalized COPD patients during a flare-up and again 8 to 16 weeks later. The goal was to measure specific immune signals (IL-17 and IL-22) to understand why COPD patients are prone to bacterial infections.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this research could point toward new ways to prevent or treat bacterial infections in COPD patients.
What could go wrong: This was a small, terminated study with only 23 participants, so results may be limited and not apply to all COPD patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

bacterial infectious disease chronic obstructive pulmonary disease COPD, severe early onset

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BACTERIAL INFECTIONS PULMONARY DISEASE, CHRONIC OBSTRUCTIVE

Contacts and locations

Locations

Roubaix hospital

Roubaix, 59100, France
Seclin hospital

Seclin, 59113, France
Tourcoing hospital

Tourcoing, 59200, France
University hospital of Lille

Lille, 59037, France

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