COPD study investigates why patients struggle to fight lung infections

NCT ID NCT02655302

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether a weak immune response to bacteria in COPD patients leads to more lung infections and flare-ups. Researchers collected sputum, blood, and nasal swabs from 23 hospitalized COPD patients during a flare-up and again 8 to 16 weeks later. The goal was to measure specific immune signals (IL-17 and IL-22) to understand why COPD patients are prone to bacterial infections.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this research could point toward new ways to prevent or treat bacterial infections in COPD patients.

What could go wrong

This was a small, terminated study with only 23 participants, so results may be limited and not apply to all COPD patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

bacterial infectious disease chronic obstructive pulmonary disease COPD, severe early onset

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Roubaix hospital

    Roubaix, 59100, France

  • Seclin hospital

    Seclin, 59113, France

  • Tourcoing hospital

    Tourcoing, 59200, France

  • University hospital of Lille

    Lille, 59037, France