Sanofi mRNA vaccine trial ends early – what we know

NCT ID NCT04798027

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested Sanofi's experimental mRNA vaccine against COVID-19 in 182 healthy adults aged 18 and older. The main goals were to check safety and measure the body's immune response. The trial was terminated early, so full results are not available.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

SARS-CoV-2 mRNA vaccine

What this could lead to

If successful, this could lead to a new mRNA vaccine option for COVID-19.

What could go wrong

This was an early (Phase 1/2) trial that was terminated, so results are limited. It is unclear if the vaccine would have been effective or safe in larger studies.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

COVID-19 prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Investigational Site Number :0360001

    Melbourne, Victoria, 3010, Australia

  • Investigational Site Number :0360002

    Nedlands, Western Australia, 6009, Australia

  • Investigational Site Number :0360003

    Morayfield, Queensland, 4506, Australia

  • Investigational Site Number :0360005

    South Brisbane, Queensland, 4101, Australia

  • Investigational Site Number :0760001

    Salvador, Estado de Bahia, 40415-006, Brazil

  • Investigational Site Number :0760003

    Belo Horizonte, Minas Gerais, 30110-063, Brazil

  • Investigational Site Number :0760004

    Campo Grande, Mato Grosso do Sul, 79070-900, Brazil

  • Investigational Site Number :3400001

    San Pedro Sula, 21104, Honduras

  • Investigational Site Number :3400002

    Barrio del Centro, 11101, Honduras

  • Investigational Site Number :8400001

    Rochester, New York, 14609, United States

  • Investigational Site Number :8400002

    Hollywood, Florida, 33024, United States

  • Investigational Site Number :8400003

    Rolling Hills Estates, California, 90274, United States

  • Investigational Site Number :8400004

    North Charleston, South Carolina, 29405, United States

  • Investigational Site Number :8400005

    Salt Lake City, Utah, 84107, United States

  • Investigational Site Number :8400006

    Miami, Florida, 33135, United States

  • Investigational Site Number :8400007

    Kansas City, Missouri, 64114, United States

  • Investigational Site Number :8400008

    Omaha, Nebraska, 68134, United States

  • Investigational Site Number :8400009

    Houston, Texas, 77081, United States

  • Investigational Site Number :8400010

    Philadelphia, Pennsylvania, 19104, United States

  • Investigational Site Number :8400015

    Knoxville, Tennessee, 37920, United States

  • Investigational Site Number :8400017

    Iowa City, Iowa, 52242, United States