Scientists investigate why ventilators may worsen lung infections

NCT ID NCT03955887

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study looked at how mechanical ventilation (breathing machines) affects the energy centers (mitochondria) of immune cells in patients with severe lung infections and acute respiratory distress syndrome (ARDS). Researchers aimed to understand why some patients get worse despite treatment. The study was terminated early and involved 28 adults. No direct treatment was given; it was purely observational to gather knowledge for future therapies.

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Conditions

The condition(s) this trial relates to.

acute respiratory distress syndrome lung disorder pneumonia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Chu Dijon Bourogne

    Dijon, 21000, France