Fatty liver drug trial in HIV patients stalls after enrolling just 4 people

NCT ID NCT05211284

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested a drug called saroglitazar magnesium for nonalcoholic fatty liver disease (NAFLD) in people with HIV. The trial aimed to see if the drug could reduce liver fat over 24 weeks. However, the study was terminated early and only enrolled 4 participants, so no meaningful results are available.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Saroglitazar magnesium

What this could lead to

If it works, this could point toward a treatment for fatty liver disease in people living with HIV.

What could go wrong

This was a very small, early-phase trial that was terminated early with only 4 participants. Results are not available, so we cannot draw any conclusions about safety or effectiveness.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

HIV infectious disease metabolic dysfunction-associated steatotic liver disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Zydus US001

    Durham, North Carolina, 27710, United States

  • Zydus US002

    Indianapolis, Indiana, 46202, United States

  • Zydus US003

    Baltimore, Maryland, 21287, United States

  • Zydus US004

    Birmingham, Alabama, 35294-2050, United States

  • Zydus US005

    La Jolla, California, 92037, United States

  • Zydus US006

    San Francisco, California, 94143, United States

  • Zydus US007

    Houston, Texas, 77030, United States

  • Zydus US008

    Richmond, Virginia, 23298, United States