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Heart drug fails to prove benefit for lung failure patients in early-stop trial

NCT ID NCT05847517

Terminated Disease control Sponsor: Consorcio Centro de Investigación Biomédica en Red (CIBER) Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether giving the heart medication metoprolol through a vein could help people with severe lung failure (ARDS) in the ICU. The goal was to see if it helped them breathe without a machine for more days. However, the trial was stopped early and only 14 people took part, so no clear conclusions can be drawn.

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Conditions

The condition(s) this trial relates to.

acute respiratory distress syndrome adult acute respiratory distress syndrome Drug-Related Side Effects and Adverse Reactions pancreatitis Pathologic Processes pneumonia Respiration Disorders Sepsis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS)

Contacts and locations

Locations

  • Complejo Hospitalario Universitario de Toledo

    Toledo, Castille-La Mancha, 45007, Spain

  • Consorci Corporació Sanitària Parc Taulí

    Barcelona, Catalonia, 08208, Spain

  • Hospital Clínic de Barcelona

    Barcelona, Catalonia, 08036, Spain

  • Hospital Clínico Universitario de Valencia

    Valencia, 46010, Spain

  • Hospital Universitario Central de Asturias

    Oviedo, Principality of Asturias, 33011, Spain

  • Hospital Universitario Clínico San Carlos

    Madrid, 28040, Spain

  • Hospital Universitario Fundación Jiménez Díaz

    Madrid, 28040, Spain

  • Hospital Universitario General de Villalba

    Madrid, 28400, Spain

  • Hospital Universitario Jerez de la Frontera

    Jerez de la Frontera, Cádiz, 11407, Spain

  • Hospital Universitario La Paz

    Madrid, 28046, Spain

  • Hospital Universitario Rey Juan Carlos

    Madrid, 28933, Spain

  • Hospital Universitario de Getafe

    Madrid, 28905, Spain

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