Which ventilator setting saves more lungs? a Head-to-Head test
NCT ID NCT07741916
First seen Aug 03, 2026 · Last updated Aug 04, 2026 · Updated 1 time
Summary
This study compares different bedside methods for choosing the optimal ventilator pressure (PEEP) in patients with moderate-to-severe acute respiratory distress syndrome (ARDS). The goal is to see if these methods give similar results and which one best balances keeping lungs open while avoiding overstretching. Researchers will analyze data from 45 ICU patients on mechanical ventilation, measuring lung mechanics and oxygenation at various PEEP levels. The findings could help standardize how doctors set ventilator pressure for ARDS patients.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Different PEEP (positive end-expiratory pressure) levels set via various bedside assessment tools
- What this could lead to
- If successful, this could identify the most reliable bedside method to set ventilator pressure, potentially improving outcomes for ARDS patients.
- What could go wrong
- This is a small observational study, so results may not apply broadly. The methods may not be interchangeable, and no single approach may emerge as clearly superior.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
CHU de Nice
Nice, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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