New hope for battling stubborn c. diff infections

NCT ID NCT02667418

First seen Nov 12, 2025 · Last updated Jun 10, 2026 · Updated 28 times

Summary

This study tested whether two specific antibiotics—fidaxomicin and a special vancomycin regimen—work better than standard vancomycin for people with repeat Clostridium difficile infections. The goal was to see which treatment best stops symptoms and prevents the infection from coming back. The study included 308 adults with confirmed C. diff and was stopped early.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Asheville VA Medical Center, Asheville, NC

    Asheville, North Carolina, 28805-2576, United States

  • Atlanta VA Medical and Rehab Center, Decatur, GA

    Decatur, Georgia, 30033-4004, United States

  • Bay Pines VA Healthcare System, Pay Pines, FL

    Bay Pines, Florida, 33744-0000, United States

  • Central Arkansas Veterans Healthcare System, Little Rock, AR

    Little Rock, Arkansas, 72205, United States

  • Clement J. Zablocki VA Medical Center, Milwaukee, WI

    Milwaukee, Wisconsin, 53295-0001, United States

  • Durham VA Medical Center, Durham, NC

    Durham, North Carolina, 27705-3875, United States

  • Edward Hines Jr. VA Hospital, Hines, IL

    Hines, Illinois, 60141-3030, United States

  • Edward Hines Jr. VA Hospital, Hines, IL

    Hines, Illinois, 60141, United States

  • James A. Haley Veterans' Hospital, Tampa, FL

    Tampa, Florida, 33612, United States

  • Jesse Brown VA Medical Center, Chicago, IL

    Chicago, Illinois, 60612, United States

  • John D. Dingell VA Medical Center, Detroit, MI

    Detroit, Michigan, 48201-1916, United States

  • Louis Stokes VA Medical Center, Cleveland, OH

    Cleveland, Ohio, 44106-1702, United States

  • Michael E. DeBakey VA Medical Center, Houston, TX

    Houston, Texas, 77030, United States

  • North Florida/South Georgia Veterans Health System, Gainesville, FL

    Gainesville, Florida, 32608-1135, United States

  • Oklahoma City VA Medical Center, Oklahoma City, OK

    Oklahoma City, Oklahoma, 73104-5007, United States

  • Phoenix VA Health Care System, Phoenix, AZ

    Phoenix, Arizona, 85012, United States

  • Rehabilitation R&D Service, Baltimore, MD

    Baltimore, Maryland, 21202, United States

  • Rocky Mountain Regional VA Medical Center, Aurora, CO

    Aurora, Colorado, 80045-7211, United States

  • South Texas Health Care System, San Antonio, TX

    San Antonio, Texas, 78229, United States

  • Southern Arizona VA Health Care System, Tucson, AZ

    Tucson, Arizona, 85723-0001, United States

  • VA Ann Arbor Healthcare System, Ann Arbor, MI

    Ann Arbor, Michigan, 48105, United States

  • VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA

    Boston, Massachusetts, 02130-4817, United States

  • VA Caribbean Healthcare System, San Juan, PR

    San Juan, 00921, Puerto Rico

  • VA Greater Los Angeles Healthcare System, West Los Angeles, CA

    West Los Angeles, California, 90073, United States

  • VA Loma Linda Healthcare System, Loma Linda, CA

    Loma Linda, California, 92357, United States

  • VA Long Beach Healthcare System, Long Beach, CA

    Long Beach, California, 90822, United States

  • VA North Texas Health Care System Dallas VA Medical Center, Dallas, TX

    Dallas, Texas, 75216-7167, United States

  • VA Northern California Health Care System, Mather, CA

    Sacramento, California, 95655-4200, United States

  • VA Palo Alto Health Care System, Palo Alto, CA

    Palo Alto, California, 94304-1290, United States

  • VA Portland Health Care System, Portland, OR

    Portland, Oregon, 97207-2964, United States

  • VA Puget Sound Health Care System Seattle Division, Seattle, WA

    Seattle, Washington, 98108, United States

  • VA Salt Lake City Health Care System, Salt Lake City, UT

    Salt Lake City, Utah, 84148, United States

  • VA San Diego Healthcare System, San Diego, CA

    San Diego, California, 92161, United States

Conditions

Explore the condition pages connected to this study.