Could a tailored antibiotic dose save more kids in the ICU?

NCT ID NCT04666948

Completed Knowledge-focused Sponsor: University Hospital, Ghent Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether giving a personalized dose of the antibiotic vancomycin to critically ill children in the ICU leads to better results than the standard approach. Researchers enrolled 314 children and compared how many reached the target drug level in their blood. The goal was to see if tailoring the dose improves treatment and reduces side effects like kidney injury.

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Conditions

The condition(s) this trial relates to.

gram-positive bacterial infections

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

VANCOMYCIN

Contacts and locations

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Locations

AZ Sint-Jan Brugge-Oostende AV

Bruges, Belgium
Cliniques universitaires de Saint Luc

Brussels, Belgium
Erasme

Brussels, Brussels Capital, Belgium
Ghent University Hospital

Ghent, Belgium
Hopital universitaire de Reine Fabiola

Brussels, Belgium
UZ Brussel

Brussels, Belgium
UZ Leuven

Leuven, Belgium