Could a pill replace IV drips for septic shock? small trial halted early
NCT ID NCT03706053
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tested whether the oral drug midodrine could help people with septic shock stop needing IV blood pressure support sooner. The trial planned to enroll many patients but was stopped early with only 10 participants. Because it was so small, we cannot draw firm conclusions about whether midodrine works for this purpose.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Midodrine Hydrochloride
- What this could lead to
- If it works, midodrine could help septic shock patients get off IV blood pressure support faster, potentially reducing ICU stays.
- What could go wrong
- This trial was terminated early with only 10 participants, so results are very limited. Midodrine may not work or could have side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Virginia
Charlottesville, Virginia, 22903, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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