Super-Sized flu shot tested for Seniors' heart and lung protection
NCT ID NCT04137887
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study compared a high-dose flu vaccine to the standard-dose shot in over 33,000 adults aged 65 and older. The goal was to see if the high-dose version could better prevent hospitalizations for heart and lung problems. The trial was terminated early, so the full picture is not available.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
High-dose quadrivalent influenza vaccine (Efluelda®)
What this could lead to
If successful, this could show that a stronger flu shot offers better protection against serious heart and lung complications in older adults.
What could go wrong
The trial was terminated early, so results are limited. It is unclear if the high-dose vaccine is truly superior for preventing hospitalizations.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for INFLUENZA (HEALTHY VOLUNTEERS) are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Investigational Site Number 2469999
Tampere, 33520, Finland