New flu vaccine shows promise in south korean trial

NCT ID NCT05144945

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This phase 3 trial tested a new recombinant flu vaccine (RIV4) against a standard inactivated flu vaccine (IIV4) in 301 healthy adults aged 18 and older in South Korea. The study measured antibody levels and safety over 29 days. The goal was to see if the new vaccine triggers a stronger immune response with similar safety.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Quadrivalent Recombinant Influenza Vaccine (RIV4)

What this could lead to

If successful, this could offer a more effective or equally protective flu vaccine option for adults, especially those 50 and older.

What could go wrong

This is a completed phase 3 trial, but results may not apply to all populations or flu seasons. The new vaccine may not prove superior to the existing one.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

influenza prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Investigational Site Number :4100001

    Seoul, Seoul-teukbyeolsi, 152-703, South Korea

  • Investigational Site Number :4100002

    Seoul, 07441, South Korea

  • Investigational Site Number :4100003

    Ansan-si, Gyeonggi-do, 15355, South Korea