Promising c. diff drug fails to prove benefit in small, halted trial

NCT ID NCT03756454

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether an extra dose of bezlotoxumab, a drug that blocks the harmful toxin made by C. diff bacteria, could help very sick patients recover after emergency colon surgery. Only 5 people took part before the study was stopped early. The goal was to see if the drug could lower the risk of death and organ failure, but there were too few participants to draw clear conclusions.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • The Ohio State University

    Columbus, Ohio, 43210, United States

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