Wolbachia-Infected mosquitoes released to fight dengue, zika, and chikungunya
NCT ID NCT06595745
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This trial tested a method to control mosquito-borne diseases like dengue, Zika, and chikungunya by releasing male Aedes aegypti mosquitoes infected with Wolbachia bacteria. These males mate with wild females, causing their eggs to die, which reduces the mosquito population. The study took place in Merida, Mexico, and involved over 15,000 residents. Unfortunately, the trial was terminated early, so its full impact is unknown.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Wolbachia-infected male Aedes aegypti mosquitoes
What this could lead to
If successful, this approach could provide a sustainable, chemical-free way to reduce or eliminate mosquito-borne diseases like dengue, Zika, and chikungunya in affected regions.
What could go wrong
The trial was terminated, so results are incomplete. Effectiveness in real-world settings remains unproven, and scaling up may face logistical or ecological challenges.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Laboratorio para el Control Biolo´gico de Aedes aegypti (LCB-UADY), Universidad Autónoma de Yucatán
Mérida, Yucatán, 97160, Mexico