Dengue danger linked to leaky gut? new study investigates

NCT ID NCT07602920

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This observational study will enroll 190 hospitalized adults with dengue in Bangladesh to see if a 'leaky gut' — where bacteria and toxins escape the intestines into the blood — is linked to severe disease. Researchers will measure gut leakage markers in blood, perform abdominal ultrasounds, and analyze gut bacteria from stool samples. The goal is to understand how gut problems might make dengue worse, but this study does not test any treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this study could reveal how gut leakage contributes to severe dengue, pointing toward new ways to predict or prevent life-threatening complications.
What could go wrong
This is an early observational study, not a treatment trial. It may find no clear link between gut leakage and disease severity, and results may not apply to all dengue patients.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Department of Medicine, Chittagong Medical College

    Chittagong, Chattogram Division, 4203, Bangladesh

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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