Gut microbes may hold key to Post-Transplant pain

NCT ID NCT06206486

First seen Aug 17, 2026 ยท Last updated Aug 17, 2026

Summary

This study investigates whether the gut microbiome and its byproducts influence chronic pain in people who have received a kidney transplant. Many transplant recipients experience persistent pain, which can affect their quality of life and treatment adherence. Researchers will track participants before and after transplant, analyzing stool and blood samples alongside pain reports, diet, and stress levels. The goal is to uncover biological mechanisms that could lead to better pain management strategies.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

What this could lead to
If successful, this research could identify gut microbiome patterns linked to pain, paving the way for future microbiome-based pain interventions in kidney transplant recipients.
What could go wrong
This is an observational study, so it cannot prove cause and effect. Results may not lead directly to treatments, and the findings might not apply to all transplant patients.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • UI Health

    RECRUITING

    Chicago, Illinois, 60612, United States

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