Michigan State University

This study tests two diet approaches—essential amino acids and a low-sugar diet—in teens aged 11-17 with fatty liver disease and heart risk. The goal is to reduce liver fat and improve health. Participants will be assigned to one or both diets over time to find the best treatment…

This study tests whether portable air filters can reduce lead dust in older homes and lower blood lead levels in children under 7. About 40 children with elevated lead levels who live in homes built before 1978 will use an air filter in their bedroom for two months. The goal is t…

This study tests a smartphone app (SFT 2.0) that uses motivational interviewing and a support person to help pregnant women stop smoking. About 790 pregnant smokers in Romania will use the app and receive counseling. The goal is to see if the app helps them quit and stay smoke-fr…

This study tests a program called Food-Body-Mind in 800 preschoolers from low-income families. The program combines mindfulness, yoga, and healthy eating lessons at school with parenting support at home. Researchers want to see if it reduces emotional and behavioral problems and …

This study compares a new, lower-energy seizure therapy (LAP-ST) to standard electroconvulsive therapy (ECT) for quickly reducing suicidal thoughts in people with depression, bipolar disorder, or schizoaffective disorder. The goal is to see if the gentler approach works just as w…

This study tests whether watching short videos made by other Vietnamese mothers can help mothers decide to get their children the HPV vaccine, which prevents certain cancers. About 60 Vietnamese American mothers with unvaccinated children aged 11-14 will be randomly assigned to w…

This pilot study tests whether a health-themed video game can encourage HPV vaccination among underserved youth aged 11-14 who have not yet received the vaccine. About 180 parent-child pairs will play the game and report their vaccination intentions and actual shots. The goal is …

This study looks at whether the ROSE program, which has been shown to prevent about half of postpartum depression cases in women at higher risk, can work for all new mothers. Researchers will enroll 2,320 pregnant women from a large health system in Detroit to see if offering the…

This study tests whether a short video can encourage college students aged 18-26 to get the HPV vaccine, which helps prevent certain cancers. About 123 students who have never received the vaccine will watch the video and report their intentions and attitudes. The goal is to find…

This study is testing whether speech amplification devices can help people with Parkinson's disease and related conditions who have a soft, weak voice (hypophonia). Researchers will work with 100 participants to measure how well these devices improve speech loudness, clarity, and…

This study is testing a program called TEACH that teaches coping skills to young people (ages 12-22) with childhood-onset lupus. The goal is to see if it helps reduce common symptoms like fatigue, pain, and depression. About 175 participants will take part, and the program is des…

This study looks at whether exercising in the morning or early evening makes a difference in lowering blood pressure and improving blood vessel health. Researchers will study 79 postmenopausal women aged 55-80 who have high blood pressure. Participants will be assigned to either …

This study tests whether combining osteopathic manipulation (a hands-on therapy) with targeted head exercises can reduce headache frequency, intensity, and duration in women with chronic cervicogenic headache—a type of headache caused by neck problems. Thirty women aged 18 to 75 …

This study tests whether a nature-based healing meditation program can help friends and family caregivers who are grieving the loss of a loved one to cancer. The program includes six audio meditation modules available online. Researchers will measure how feasible and acceptable t…

This study looks at how using single words or short phrases (instead of full sentences) affects language processing and word learning in young children with autism, ages 1 to 4. Researchers will show children screen-based tasks and track their eye movements to see which type of l…

This study looks at how using very short, simple sentences (like single words or telegraphic speech) affects how young children with Down syndrome process language and learn new words. Researchers will show children pictures and play recordings of different types of sentences to …

This study is testing a new rapid diagnostic device called In-Dx to quickly identify infections and antibiotic resistance in emergency patients with suspected sepsis. Researchers will compare the device's results to standard lab cultures using stored samples from 2,500 patients. …

This study follows 120 children aged 3-6 who stutter or have typical speech, to learn why some recover naturally. Kids complete speech tests, wear brain-monitoring caps, and speak in virtual reality classrooms. Researchers track brain activity, heart rate, and skin responses to f…

This study looks at whether messages designed specifically for African American parents can help them feel more ready to give their daughters the HPV vaccine. About 265 parents with daughters aged 8-17 who haven't had the vaccine yet will take part. Some parents will see cultural…

This study tests whether adjusting room light during labor can improve uterine contractions and reduce the need for C-sections. Researchers will monitor 100 pregnant women, using different light settings (bright, dim, or red light) to see how it affects contractions and melatonin…