Could papaya leaves help fight dengue? new trial tests the idea

NCT ID NCT06121934

Completed Disease control Sponsor: Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether an extract from papaya leaves (CPLE) can help people with dengue fever. 250 adults with confirmed dengue were given either CPLE capsules or a placebo for 5 days. The main goals were to see if the extract could raise platelet counts and reduce the risk of severe disease. The trial is now complete, and results will show if this natural remedy has real benefits.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Carica papaya leaf extract (CPLE) capsules
What this could lead to: If it works, this could offer a simple, plant-based option to help manage dengue and prevent severe complications.
What could go wrong: This is a completed phase 3 trial, but results are not yet widely confirmed. The extract may not significantly improve outcomes, and individual responses can vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

dengue disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DENGUE

Contacts and locations

Locations

Bangabandhu Sheikh Mujib Medical University

Dhaka, 1200, Bangladesh

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