Can existing COVID drug beat dengue? new trial begins

NCT ID NCT06551844

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 2 trial is testing two antivirals—molnupiravir (used for COVID-19) and a lab-made antibody called VIS513—in 500 people with early dengue. Participants must have had fever for less than 48 hours and a positive rapid test. The goal is to see if these drugs can clear the dengue virus faster and reduce symptoms, while also checking for side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

molnupiravir (an antiviral drug) and VIS513 (a monoclonal antibody)

What this could lead to

If successful, this could point toward a treatment that shortens dengue illness and reduces severe complications.

What could go wrong

This is an early phase 2 trial with only 500 participants, so results may not apply to all dengue patients. The drugs may not speed up recovery or could cause side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

dengue disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hospital for Tropical Diseases, Ho Chi Minh city

    RECRUITING

    Ho Chi Minh City, 700000, Vietnam

    Contact

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  • Universiti Malaya Medical Centre

    NOT_YET_RECRUITING

    Kuala Lumpur, 59100, Malaysia

    Contact