Chikungunya vaccine shows promise for teens in landmark trial

NCT ID NCT04650399

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a single-dose chikungunya vaccine (VLA1553) in about 750 teenagers aged 12 to 17. The goal was to see if the vaccine safely produces enough antibodies to protect against the virus. Participants received either the vaccine or a placebo, and their immune responses were tracked for a year.

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Conditions

The condition(s) this trial relates to.

chikungunya prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Associação Obras Sociais Irmã Dulce / Centro de Pesquisa Clínica - CPEC

    Salvador, Estado de Bahia, 40415-180, Brazil

  • CECOR - Centro Oncológico de Roraima

    Boa Vista, Acre, 69304-015, Brazil

  • Centro de Estudos do Instituto de Infectologia Emílio Ribas

    São Paulo, 01246-900, Brazil

  • Centro de Pesquisa Clínica da Faculdade de Medicina da Universidade Federal de Mato Grosso do Sul - UFMS

    Campo Grande, 79070-900, Brazil

  • Centro de Pesquisa e Desenvolvimento de Fármacos (CPDF) - Universidade Federal de Minas Gerais, Instituto de Ciências Biológicas

    Belo Horizonte, Minas Gerais, 31270-010, Brazil

  • Centro de Pesquisas Clínicas Universidade Federal Sergipe

    Aracaju, Sergipe, 49100-000, Brazil

  • Faculdade de Medicina de São José do Rio Preto - FAMERP

    São José do Rio Preto, São Paulo, 15090-000, Brazil

  • Fundação de Medicina Tropical Dr. Heitor Vieira Dourado

    Manaus, Amazonas, 69040-000, Brazil

  • Núcleo de Medicina Tropical - Universidade Federal do Ceará

    Fortaleza, Ceará, 60020-181, Brazil

  • Real Hospital Português de Beneficência em Pernambuco

    Recife, Pernambuco, 52010-075, Brazil