Timing of dialysis in septic shock: early vs. delayed – study halted early
NCT ID NCT01682590
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at 500 adults with septic shock and severe acute kidney injury to see if starting dialysis early (within 12 hours) or waiting (48-60 hours) affected survival at 90 days. The trial was terminated early, so the results are not conclusive. The goal was to find the best timing for dialysis in critically ill patients.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
dialysis (renal replacement therapy)
What this could lead to
If successful, this could help doctors decide the best time to start dialysis for patients with septic shock and kidney failure, potentially improving survival.
What could go wrong
The trial was terminated early, so results are limited. It is unclear whether early or delayed dialysis is better, and findings may not apply to all patients.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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CH Avignon
Avignon, 84000, France
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CH Belfort
Belfort, 90000, France
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CH Dieppe
Dieppe, 76200, France
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CH Périgueux
Périgueux, 24019, France
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CH Sud Essonne - Site Etampes
Étampes, 91 150, France
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CH de BOURG-EN-BRESSE
Bourg-en-Bresse, 01012, France
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CH de LA ROCHE sur YON
La Roche-sur-Yon, 85000, France
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CHG Mulhouse
Mulhouse, 68100, France
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CHR Metz
Thionville, 57100, France
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CHR d'Orléans
Orléans, 45100, France
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CHRU Tours
Tours, France
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CHU Besançon
Besançon, 25000, France
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CHU Caen
Caen, 14003, France
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CHU Clermont-Ferrand
Clermont-Ferrand, 63100, France
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CHU Dijon
Dijon, 21000, France
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CHU Grenoble
Grenoble, 38043, France
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CHU Lapeyronie
Montpellier, 34295, France
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CHU Lyon Sud
Pierre-Bénite, 69495, France
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CHU Montpellier
Montpellier, 34000, France
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CHU Nancy Brabois
Nancy, 54000, France
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CHU Nîmes
Nîmes, 30000, France
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CHU de Lyon
Lyon, 69000, France
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CHU de Strasbourg - Nouvel hôpital civil
Strasbourg, 67000, France
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Groupe Hospitalier de l'institut Catholique de LILLE
Lille, 59160, France
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HOPITAL BICHAT Claude-Bernard
Paris, 75018, France
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Hôpital Cochin
Paris, 75014, France
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Hôpital Raymond-Poincaré GARCHES (AP-HP)
Garches, 92380, France