Could a simple mineral cut the need for powerful blood-pressure drugs in septic shock?
NCT ID NCT07716956
First seen Jul 21, 2026 · Last updated Jul 22, 2026 · Updated 1 time
Summary
This trial investigates whether keeping magnesium levels in the upper normal range can lower the amount and duration of norepinephrine, a drug that raises blood pressure, in adults with septic shock. Participants are randomly assigned to receive individualized magnesium infusions or standard care. Researchers will track total norepinephrine use, ICU stay length, breathing-tube duration, and survival.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- intravenous magnesium sulfate infusions to achieve upper normal serum magnesium levels
- What this could lead to
- If it works, this could point toward a simple, low-cost way to reduce the amount of blood-pressure medication needed in septic shock, potentially shortening ICU stays.
- What could go wrong
- This is a small, early-stage trial with only 60 participants, so results may not apply broadly. The intervention may not lower medication needs or improve survival, and magnesium infusions carry risks like low blood pressure or heart rhythm issues.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Alexandria Main University Hospital
Alexandria, Alexandria Governorate, 21526, Egypt
Contact Phone: •••-•••-•••• Email: •••••@•••••
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