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Could a key hormone be missing in septic shock?

NCT ID NCT07721974

Not yet recruiting Knowledge-focused Sponsor: Assistance Publique - Hôpitaux de Paris Source: ClinicalTrials.gov ↗

First seen Jul 23, 2026 · Last updated Jul 24, 2026 · Updated 1 time

Summary

Septic shock is a life-threatening condition with high mortality. This study investigates whether patients with septic shock have a deficiency of angiotensin II, a hormone that helps regulate blood pressure. Researchers will measure hormone levels in blood and urine samples from 320 adults with septic shock, as well as from patients with less severe infections or other types of shock. The goal is to determine how common this deficiency is and whether it is specific to septic shock.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If this study confirms that many septic shock patients have low angiotensin II, it could support using angiotensin II as a targeted treatment.
What could go wrong
This is an observational study, not a treatment trial. It will measure hormone levels but cannot prove that correcting them improves outcomes.

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Conditions

The condition(s) this trial relates to.

cardiogenic shock infectious disease with sepsis toxic shock syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SEPTIC SHOCK

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

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