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Nasal spray vaccine aims to shield children from RSV

NCT ID NCT04919109

Terminated ⭐️ VACCINE ⭐️ Sponsor: Codagenix, Inc Source: ClinicalTrials.gov ↗

First seen Jul 15, 2026 · Last updated Jul 16, 2026 · Updated 1 time

Summary

This early-stage trial tests an experimental RSV vaccine called CodaVax-RSV, given as nose drops, in healthy children aged 6 months to 5 years. The study evaluates the vaccine's safety and the immune response it triggers. Some children receive the vaccine at different doses, while others get a placebo (saline nose drops). Participants are monitored closely for side effects and antibody levels.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
a live attenuated vaccine against RSV called CodaVax-RSV, given as nose drops
What this could lead to
If successful, this could lead to a safe and effective vaccine to protect children from RSV, a common but potentially serious respiratory virus.
What could go wrong
This is an early Phase 1 trial with a small number of participants, so the vaccine may not prove safe or effective in larger studies. Side effects are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

respiratory tract infectious disorder respiratory syncytial virus infectious disease prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

RESPIRATORY SYNCYTIAL VIRUS INFECTIONS

Contacts and locations

Locations

  • University of Witwatersrand (WITS)/Vaccines and Infectious Diseases Analytics (VIDA)

    Johannesburg, South Africa

  • Velocity

    Lincoln, Nebraska, 658510, United States

  • Velocity

    Omaha, Nebraska, 68134, United States

  • Velocity

    Providence, Rhode Island, 02818, United States

  • Velocity

    West Jordan, Utah, 84088, United States

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