A 5-Minute ultrasound could reveal how sick a Baby's lungs really are
NCT ID NCT07778225
First seen Aug 21, 2026 · Last updated Aug 21, 2026
Summary
This study tests whether a quick, bedside ultrasound of the internal jugular vein in the neck can help tell how severe bronchiolitis is in infants aged 1 to 23 months. Researchers will measure how much the vein's diameter changes with breathing and compare that to standard clinical severity scores, oxygen levels, and need for intensive care. No treatment is given—the ultrasound is added to usual care to see if it can serve as a reliable marker of disease severity.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Point-of-care ultrasonography (POCUS) measuring internal jugular vein diameter variation
- What this could lead to
- If it works, this could give doctors a quick, non-invasive way to gauge bronchiolitis severity in infants, helping guide treatment decisions.
- What could go wrong
- This is an observational study, so it can only show a link, not prove cause. The ultrasound technique may not reliably predict severity in all infants, and results may not apply beyond this specific setting.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 120 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2026
An estimate. Start dates often move.
- Expected to finish
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Aug 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Infants aged 1 to 23 months presenting to the Pediatric Emergency Department with a clinical diagnosis of acute bronchiolitis according to the American Academy of Pediatrics (AAP) clinical criteria will be prospectively enrolled. Eligible participants will be evaluated within the first 6 hours of emergency department presentation after written informed consent is obtained from a parent or legal guardian. Participants will undergo standardized clinical severity assessment and point-of-care ultrasonography of the internal jugular vein, lungs, and diaphragm in addition to routine clinical care. No study-specific therapeutic intervention will be assigned.
- Ages
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1 month to 23 months
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Infants aged 1-23 months * Clinical diagnosis of acute bronchiolitis per AAP (2014) criteria (first wheezing episode following an upper respiratory infection prodrome, with tachypnea, retractions, and/or crackles) * Written informed consent obtained from parent/legal guardian * Evaluable within the first 6 hours of emergency department presentation Exclusion Criteria: * Underlying congenital heart disease * Chronic lung disease (bronchopulmonary dysplasia, cystic fibrosis) * Prior history of recurrent wheezing/suspected asthma * Anatomical abnormality of the neck or prior history of central venous catheterization or jugular vein thrombosis * Hemodynamic instability/shock * Immediate need for intubation/mechanical ventilation precluding ultrasound assessment * Parent/legal guardian declines consent
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Eskisehir Osmangazi University Faculty of Medicine, Pediatric Emergency Department
Eskişehir, Eskişehir, 26480, Turkey (Türkiye)
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