New antiviral pill aims to shorten RSV symptoms in vulnerable adults

NCT ID NCT07658534

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests an oral antiviral called ziresovir (AK0529) in adults at high risk for severe RSV infection, such as those with chronic lung or heart disease, weakened immune systems, or age 65 and older. Participants receive either the drug or a placebo, and researchers measure how quickly lower respiratory symptoms like cough, wheezing, and shortness of breath improve. The goal is to see if ziresovir can speed recovery and reduce the burden of RSV in this vulnerable group.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ziresovir (AK0529)

What this could lead to

If it works, this could provide a treatment to reduce severe RSV symptoms in vulnerable adults, potentially preventing hospitalizations.

What could go wrong

This is a mid-stage trial with 290 participants, so results may not confirm effectiveness. The drug may cause side effects or fail to outperform placebo.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

heart disorder respiratory syncytial virus infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cangzhou Hospital of Integrated TCM-WM

    RECRUITING

    Cangzhou, Hebei, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • China-Japan Friendship Hospital

    RECRUITING

    Beijing, Beijing Municipality, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Guangzhou Medical University Panyu Central Hospital

    NOT_YET_RECRUITING

    Guangzhou, Guangdong, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Henan Infectious Disease Hospital (The Sixth People's Hospital of Zhengzhou)

    NOT_YET_RECRUITING

    Zhengzhou, Henan, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • People's Hospital of Rui'an City

    RECRUITING

    Rui’an, Zhejiang, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Taizhou Hospital of Zhejiang Province

    RECRUITING

    Taizhou, Zhejiang, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Affiliated Hospital of Nanyang Medical College

    RECRUITING

    Nanyang, Henan, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Wuhan Sixth Hospital

    RECRUITING

    Wuhan, Hubei, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Zhejiang Hospital

    NOT_YET_RECRUITING

    Hangzhou, Zhejiang, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••