Common diabetes and acne drugs studied for head and neck cancer treatment

NCT ID NCT03076281

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested whether metformin (a diabetes drug) and doxycycline (an antibiotic) could help treat head and neck cancer when taken before surgery. The trial aimed to see if these drugs could change certain proteins in the tumor's supportive tissue. Only 7 people took part before the study was stopped early, so results are very limited.

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Conditions

The condition(s) this trial relates to.

disorder of pharynx head and neck squamous cell carcinoma laryngeal disorder lymphoid interstitial pneumonia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Sidney Kimmel Cancer Center at Thomas Jefferson University

    Philadelphia, Pennsylvania, 19107, United States