Could a simple mouthwash protect cancer patients from Radiation's painful side effects?
NCT ID NCT06251050
First seen Aug 13, 2026 · Last updated Aug 14, 2026 · Updated 1 time
Summary
This trial tests whether a mouthwash containing lithium can prevent or reduce oral mucositis (painful mouth sores) and dysgeusia (taste changes) in people receiving radiation for head and neck tumors. Participants will rinse with either a lithium mouthwash or a placebo during their radiotherapy course. The study aims to see if the mouthwash lowers the chance of severe mouth sores and improves quality of life.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- lithium-containing mouthwash
- What this could lead to
- If effective, this mouthwash could offer a simple, low-cost way to reduce severe mouth sores and taste problems during radiotherapy, improving quality of life for head and neck cancer patients.
- What could go wrong
- This is an early-phase trial, so the mouthwash may not prove more effective than placebo. Possible side effects include irritation or allergic reactions, and results may not apply to all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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West China Hospital, Sichuan University
Chengdu, Sichuan, 610041, China
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