Can a scan tell who needs more surgery after head and neck cancer?

NCT ID NCT05707078

First seen Aug 12, 2026 · Last updated Aug 13, 2026 · Updated 1 time

Summary

This study looks at whether PET/CT scans can accurately detect remaining cancer in lymph nodes after a person has completed curative radiation for head and neck cancer. About 600 adults who finished treatment will receive a PET/CT scan, and those with suspicious findings may undergo neck dissection to remove affected lymph nodes. The goal is to see how well the scan identifies which patients actually have malignant cells, potentially guiding future follow-up care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
PET/CT imaging with FDG tracer, followed by neck dissection if needed
What this could lead to
If PET/CT proves reliable, it could guide which patients truly need neck dissection, reducing unnecessary surgeries.
What could go wrong
The test may miss small tumors or give false alarms, and the study's results depend on how well the scans predict actual findings during surgery.

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Conditions

The condition(s) this trial relates to.

head and neck squamous cell carcinoma Squamous Cell Carcinoma of Head and Neck

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Department of Otorhinolaryngology, Head & Neck Surgery and Audiology, Rigshospitalet

    RECRUITING

    Copenhagen, Copenhagen, 2100, Denmark

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