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Scientists probe mysterious loss of nose immune cells in aging

NCT ID NCT06039527

Recruiting now Knowledge-focused Sponsor: Leiden University Medical Center Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This observational study aims to understand why older adults lose certain immune cells (T cells) from their nasal passages, which may make them more prone to respiratory infections. Researchers will compare young adults (18-30), healthy older adults (65+), and frail older adults (65+) by taking nasal samples and blood tests. The goal is to uncover the mechanisms behind this cell loss and its link to infection risk, but this study does not test any treatment or intervention.

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Conditions

The condition(s) this trial relates to.

respiratory tract infectious disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AGING RESPIRATORY TRACT INFECTIONS

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Leiden University Medical Center

    RECRUITING

    Leiden, South Holland, 2333ZA, Netherlands

    Contact

    Contact

    Contact

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••