MRI scans aim to uncover hidden ear damage in CMV survivors

NCT ID NCT05229744

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether people born with cytomegalovirus (CMV) infection who have hearing loss or balance problems also have a condition called endolymphatic hydrops (fluid buildup in the inner ear). Researchers used a special MRI scan with a contrast dye to check for this fluid. The study was small and ended early, but it may help clarify the link between congenital CMV and inner ear issues.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Gadovist® (gadobutrol, a contrast agent for MRI)

What this could lead to

If successful, this could help doctors understand why some people with congenital CMV develop hearing loss or balance problems, potentially guiding future treatments.

What could go wrong

This was a small, terminated study with only 18 participants, so results may be limited and not apply to everyone. MRI contrast agents carry a small risk of allergic reaction or kidney issues.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

endolymphatic hydrops fetal cytomegalovirus syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hôpital Fondation Adolphe de Rothschild

    Paris, PARIS, 75019, France

  • Hôpital Robert Debre

    Paris, 75019, France