Cure My Disease

Don't miss your cure!

 Log in / Sign up

Experimental drug aims to keep viral pneumonia patients out of hospital

NCT ID NCT06202521

Terminated Disease control Sponsor: Senhwa Biosciences, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This Phase 2 trial tested the drug silmitasertib (CX-4945) plus standard care in adults with pneumonia caused by COVID-19 or influenza. The goal was to see if the drug could reduce the need for hospitalization or prevent death. The study planned to enroll 120 people but was terminated early after enrolling 45. Participants took the drug or a placebo twice daily for up to 5 days.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
silmitasertib (CX-4945)
What this could lead to
If it worked, this could point toward a new treatment to prevent hospitalization and death from viral pneumonia caused by COVID-19 or flu.
What could go wrong
The trial was terminated early with only 45 participants, so results are limited. It is a Phase 2 study, meaning it is still early and may not show clear benefit or safety.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for COMMUNITY-ACQUIRED PNEUMONIA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Community-Acquired Pneumonia COVID-19 influenza pneumonia viral pneumonia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COMMUNITY-ACQUIRED PNEUMONIA INFLUENZA WITH PNEUMONIA SARS-COV-2 -ASSOCIATED PNEUMONIA

Contacts and locations

Locations

  • Far Eastern Memorial Hospital

    New Taipei City, Taiwan

  • Kaohsiung Veterans General Hospital

    Kaohsiung City, Taiwan

  • National Taiwan University Cancer Center, National Taiwan University Hospital

    Taipei, Taiwan

  • National Taiwan University Hospital

    Taipei, Taiwan

  • Taichung Veterans General Hospital

    Taichung, Taiwan

  • Taoyuan General Hospital, Ministry of Health and Welfare

    Taoyuan, Taiwan

  • Tri-Service General Hospital

    Taipei, Taiwan

More trials for these conditions

Other studies related to the condition(s) this trial covers.